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TranscriptomicsOn the mode of anti-C. albicans activity of a bis(benzoxaborole) analogue of Tavaborole
We presented the pharmacodynamic relationship between benzoxaborole concentrations and Candida albians blastoconidial population dynamics. Bis(benzoxaborole) analogue (2) and Tavaborole (ref.) showed comparable moderate effects against C. albicans (time-kill kinetic assays). Benzoxaboroles inhibited...
ORGANISM(S): Candida albicans 
2026-04-30 | GSE296032 | GEO
GenomicsGenomic sequencing of T. brucei cell lines resistant to AN7973
Wild type T. brucei bloodstream form were incubated with increasing concentrations of AN7973, a benzoxaborole compound developed by Anacor Pharmaceuticals Inc. against Animal African Trypanosomiasis. Cells had a tendency to lose resistance, only roughly 2x EC50 resistance was obtained. This experime...
ORGANISM(S): Trypanosoma brucei brucei 
2018-06-04 | E-MTAB-6307 | biostudies-arrayexpress
GenomicsOn the mode of anti-C. albicans activity of a bis(benzoxaborole) analogue of Tavaborole
On the mode of anti-C. albicans activity of a bis(benzoxaborole) analogue of Tavaborole
PRJNA1257337 | ENA
GenomicsTrypanosoma brucei transcriptome changes upon exposure to the aminomethyl-benzoxaborole AN3057
Trypanosoma brucei transcriptome changes upon exposure to the aminomethyl-benzoxaborole AN3057
PRJEB72886 | ENA
UnknownA Novel Benzoxaborole Is Active against Escherichia coli and Binds to FabI.
Not available
S-EPMC8370241 | biostudies-literature
UnknownDiscovery of novel benzoxaborole-based potent antitrypanosomal agents.
Not available
S-EPMC4007846 | biostudies-literature
UnknownDye Displacement Assay for Saccharides using Benzoxaborole Hydrogels.
Not available
S-EPMC5838390 | biostudies-literature
MetabolomicsHost-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles
Recent development of benzoxaborole-based chemistry gave rise to a collection of compounds with great potential in targeting diverse infectious diseases, including human African Trypanosomiasis (HAT), a devastating neglected tropical disease. However, further medicinal development is largely restric...
2018-02-12 | MTBLS452 | MetaboLights
UnknownDiscovery of New 7-Propanamide Benzoxaborole as Potent Anti-SKOV3 Agent via 3D-QSAR Models.
Not available
S-EPMC12786075 | biostudies-literature
UnknownAggregation-Based Bacterial Separation with Gram-Positive Selectivity by Using a Benzoxaborole-Modified Dendrimer.
Not available
S-EPMC9958924 | biostudies-literature
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