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TranscriptomicsExpression data from wild type, Ring1B-/-, Eed-/-, and Ring1B/Eed double deficient mouse ES cells
Polycomb complexes establish chromatin modifications for maintaining gene repression and are essential for embryonic development in mice. Here we use pluripotent embryonic stem (ES) cells to demonstrate an unexpected redundancy between Polycomb repressive complex 1 (PRC1) and PRC2 during the formati...
ORGANISM(S): Mus musculus 
2009-11-30 | E-GEOD-19076 | biostudies-arrayexpress
TranscriptomicsMicroarray gene expression data in liver, gonadal adipose tissue, pancreatic islets, and skeletal muscle in two lines of the Berlin Fat Mouse (BFMI861-S1 and BFMI861-S2)
The Berlin Fat Mouse Inbred line (BFMI) is a model for obesity and the metabolic syndrome. This study aimed to identify genetic variants associated with liver weight, liver triglycerides, and body weight using the obese BFMI sub-line BFMI861-S1. BFMI861-S1 mice are insulin resistant and store ectopi...
ORGANISM(S): Mus musculus 
2022-03-27 | E-MTAB-11512 | biostudies-arrayexpress
UnknownFrailty and the Metabolic Syndrome - Results of the Berlin Aging Study II (BASE-II).
Not available
S-EPMC12275811 | biostudies-literature
ProteomicsMutations in NDUFS1 Cause Metabolic Reprogramming and Disruption of the Electron Transfer
Complex I (CI) is the first enzyme of the mitochondrial respiratory chain and couples the electron transfer with proton pumping. Mutations in genes encoding CI subunits can frequently cause inborn metabolic errors. We applied proteome and metabolome profiling of patient-derived cells harboring patho...
ORGANISM(S): Homo sapiens (Human) 
2019-10-16 | PXD009743 | Pride
Proteome profiling Ndufs1 Metabolome profiling Mt-nd5 Mitochondrial complex i 
UnknownAssociation Between Dispatch of Mobile Stroke Units and Functional Outcomes Among Patients With Acute Ischemic Stroke in Berlin.
Not available
S-EPMC7856548 | biostudies-literature
UnknownPhasic left atrial strain to predict worsening of diastolic function: Results from the prospective Berlin Female Risk Evaluation follow-up trial.
Not available
S-EPMC9986257 | biostudies-literature
UnknownOff-label-dosing of non-vitamin K-dependent oral antagonists in AF patients before and after stroke: results of the prospective multicenter Berlin Atrial Fibrillation Registry.
Not available
S-EPMC8739306 | biostudies-literature
ProteomicsRenal oncocytoma characterized by the defective complex I of the respiratory chain boosts the synthesis of the ROS scavenger glutathione
Renal oncocytomas are rare benign tumors of the kidney and are characterized by a deficient complex I (CI) enzyme activity of the oxidative phosphorylation (OXPHOS) system caused by mitochondrial DNA (mtDNA) mutations. Yet, little is known about the underlying molecular mechanisms and alterations of...
ORGANISM(S): Homo sapiens (Human) 
2017-11-21 | PXD007633 | Pride
Renal oncocytoma - complex i deficiency - glutathione metabolism - mtdna mutation 
UnknownCost-effectiveness of short-term parent-infant-psychotherapy, results from two randomized controlled trials.
Not available
S-EPMC12837010 | biostudies-literature
TranscriptomicsHepatic gene expression profiles after long-term high-fat diet feeding in wild type and Nrf2 knock-out mice.
To assess the role of the transcription factor NFE2 related factor 2 like 2 ( Nrf2) in the development of high-fat diet (HFD)-induced obesity and non-alcoholic HFD-induced fatty liver disease, 8 wild type (WT) and 8 Nrf2 knock-out (Nrf2-KO) C57BL6J male mice (obtained from Riken BRC, Tsukuba, Japan ...
ORGANISM(S): Mus musculus 
2011-11-30 | E-GEOD-33575 | biostudies-arrayexpress
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