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TranscriptomicsGenotyping of human glioma 11
Characterization of MYC amplification in a glioma by SNParray
ORGANISM(S): Homo sapiens 
2013-05-31 | E-MEXP-3285 | biostudies-arrayexpress
TranscriptomicsLoss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis (Affymetrix)
DNA methylation is tightly regulated throughout mammalian development and altered methylation patterns are a hallmark of cancer. The methylcytosine dioxygenase TET2 is frequently mutated in acute myeloid leukemia (AML) and has been suggested to protect CpG islands and promoters from aberrant methyla...
ORGANISM(S): Mus musculus 
2015-04-22 | E-GEOD-59586 | biostudies-arrayexpress
GenomicsTET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS
TET proteins convert 5-methylcytosine to 5-hydroxymethylcytosine, an emerging dynamic epigenetic state of DNA that can influence transcription. Evidence has linked TET1 function to epigenetic repression complexes, yet mechanistic information, especially for the TET2 and TET3 proteins, remains limite...
ORGANISM(S): Mus musculus 
2013-02-07 | E-GEOD-36620 | biostudies-arrayexpress
TranscriptomicsIGR_U985_CLL_EGR2_GE_STUDY_OB
Chronic lymphocytic leukemia (CLL), the most frequent adult leukemia in western countries, is a clonal accumulation of mature B-lymphocytes and its natural history is yet unclear. By using sequencing and cellular biology approaches on a cohort of CLL patient samples, we show here that acquired CLL m...
ORGANISM(S): Mus musculus 
2014-06-18 | E-MTAB-1764 | biostudies-arrayexpress
UnknownInteractions between Severe Acute Respiratory Syndrome Coronavirus 2 Replication and Major Respiratory Viruses in Human nasal Epithelium.
Not available
S-EPMC9452145 | biostudies-literature
GenomicsInstitut Curie Neuroblastoma data access Committee
Data Access Committee EGAC00001000319
EGAC00001000319 | EGA
MetabolomicsGNPS - Cyanobacterial strains from Guadeloupe mangroves
LC-MS/MS analyses of 20 MeOH/ACN/water cyanobacterial extracts from Guadeloupe mangroves in the DDA mode. ESI +
ORGANISM(S): Arthrospira Sp. (ncbitaxon:35824) Nodosilinea N. Sp. Oscillatoria Sp. (ncbitaxon:1159) Jaaginema Sp. Limnothrix N. Sp. Scytonema Cf. Mirabile Er0515.01 Synechocystis Sp. (ku951820)/92% Lyngbya N. Sp. 
MSV000090244 | GNPS
TranscriptomicsRNAi knock-down of MKL1 in human megakaryocytes derived from cord blood or cytapheresis
Characterize the genes regulated by MKL1/SRF complex in human megakaryocytes (MKs) derived from cord blood or cytapheresis : Using a knock down approach by small interference of MKL1 in MK progenitors, we observed a decrease in the percentage of cells with actin polymerization after adhesion on vari...
ORGANISM(S): Homo sapiens 
2009-09-14 | E-TABM-640 | biostudies-arrayexpress
TranscriptomicsIGR_Itzykson_CMML
Genomic studies in chronic myeloid malignancies, including myeloproliferative neoplasms (MPN), myelodysplastic syndromes (MDS) and MPN/MDS, have identified common mutations in genes encoding signaling, epigenetic, transcription and splicing factors. Analysis of 18 of these genes in a cohort of 224 c...
ORGANISM(S): Homo sapiens 
2013-01-17 | E-MTAB-1044 | biostudies-arrayexpress
UnknownRandomized phase III trial of metabolic imaging-guided dose escalation of radio-chemotherapy in patients with newly diagnosed glioblastoma (SPECTRO GLIO trial).
Not available
S-EPMC10768994 | biostudies-literature
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