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GenomicsThe chromatin remodeler ATRX binds to atypical chromatin domains at the 3’ exons of ZNF genes to preserve H3K9me3 enrichment
Here, we report that ATRX co-localizes with the H3K9-methyl transferase SETDB1 (also known as ESET), the co-repressor TRIM28 (also known as KAP1), and the transcription factor ZNF274 at 3’ exons of Zinc Finger Genes (ZNFs) containing an atypical H3K9me3/H3K36me3 chromatin signature. Disruption of ...
ORGANISM(S): Homo sapiens 
2016-04-05 | E-GEOD-70920 | biostudies-arrayexpress
UnknownThe Prevalence of Symptomatic Dermographism: Results of the International UCARE PREVALENCE-D Study.
Not available
S-EPMC12862545 | biostudies-literature
MetabolomicsGut Microbiome Composition Is Associated With Future Onset of Crohn's Disease in Healthy First-Degree Relatives.

BACKGROUND & AIMS: The cause of Crohn's disease (CD) is unknown, but the current hypothesis is that microbial or environmental factors induce gut inflammation in genetically susceptible individuals, leading to chronic intestinal inflammation. Case-control studies of patients...

2023-11-16 | MTBLS300 | MetaboLights
UnknownPhase II trial of trastuzumab in combination with cytotoxic chemotherapy for treatment of metastatic osteosarcoma with human epidermal growth factor receptor 2 overexpression: a report from the children's oncology group.
Not available
S-EPMC3397787 | biostudies-literature
UnknownInternationale Umfrage zur Behandlungspraktiken bei atopischer Dermatitis bei schwangeren und stillenden Frauen: Perspektiven von Arzten
Not available
S-EPMC12435109 | biostudies-literature
MetabolomicsPRDM15 is a master regulator of metabolism essential to sustain B-cell lymphomagenesis
PRDM family members are sequence-specific transcriptional regulators involved in cell identity and fate determination and are often dysregulated in cancer. The PRDM15 gene is of particular interest, given its relatively low expression in adult tissues and its overexpression in follicular lymphomas (...
2025-06-16 | MTBLS1639 | MetaboLights
UnknownEpstein-Barr virus-associated post-transplant lymphoproliferative disorders in pediatric transplantation: A prospective multicenter study in the United States.
Not available
S-EPMC11115376 | biostudies-literature
UnknownACE overexpression in myeloid cells increases oxidative metabolism and cellular ATP.
Not available
S-EPMC6996878 | biostudies-literature
UnknownMyeloid cell ACE shapes cellular metabolism and function in PCSK-9 induced atherosclerosis.
Not available
S-EPMC10623052 | biostudies-literature
TranscriptomicsTranscription profiling of mouse embryonic stem cell-derived astrocytes
Expression profiles for Gfap-positive astrocytes obtained by in vitro differentiation of 129SvJae x C57BL/6 murine embryonic stem (ES) cells. Generated to examine the relationship between expression levels and DNA methylation patterns. Experiment Overall Design: 3 replicates of ES-derived astrocyte...
ORGANISM(S): Mus musculus 
2008-10-20 | E-GEOD-11483 | biostudies-arrayexpress
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