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TranscriptomicsTransposable element expression at unique loci in single cells with CELLO-seq
We introduce a novel method (CELLO-seq) for long-read RNA sequencing at single cell resolution. CELLO-seq allows for full-length RNA sequencing and enables measurement of allelic, isoform and Transposable Element (TE) expression at unique loci. We use CELLO-seq to assess the widespread expression of...
ORGANISM(S): Homo sapiens 
2020-10-01 | E-MTAB-9577 | biostudies-arrayexpress
TranscriptomicsAffymetrix gene expression array (mouse 2.0) of sorted undifferentiated spermatogonia in inducible Miwi2 knock-out model
Undifferentiated spermatogonia were sorted from Miwi2Tom/FL; ERT-Cre/+ (Miwi2-iKO) and Miwi2Tom/+; ERT-Cre/+ (Miwi2-CTL) mice injected with tamoxifen two weeks after last tamoxifen injection to understand an impact of acute Miwi2 deletion on spermatogenic homeostasis.
ORGANISM(S): Mus musculus 
2018-03-21 | E-MTAB-6612 | biostudies-arrayexpress
GenomicsTEX15 is an essential executor of MIWI2-directed transposon DNA methylation and silencing.
The PIWI protein MIWI2 and its associated PIWI-interacting RNAs (piRNAs) instruct DNA methylation of young active transposable elements (TEs) in the male germline. Here we show that MIWI2 associates with TEX15 in foetal gonocytes. TEX15 is predominantly a nuclear protein that is not required for piR...
ORGANISM(S): Mus musculus 
2020-06-17 | E-MTAB-9090 | biostudies-arrayexpress
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