Sort   by:  
 Page size 
ProteomicsKinome profiling of venetoclax-resistant wild type and NRAS-G12C MOLM-14 cells
Despite efficacy of FLT3 and BCL2 inhibition in acute myeloid leukemia (AML), relapse limits survival. Mutation status and AML monocytic differentiation are implicated in resistance. On-treatment tumor evolution may select for genetically distinct clones or shifts in differentiation not resolvable ...
ORGANISM(S): Homo sapiens (Human) 
2026-06-15 | PXD068585 | Pride
Venetoclax Gilteritinib Kinase Inhibitor Bead Aml 
ProteomicsQuantitative analysis of non histone lysine methylation sites and lysine demethylases in breast cancer cell lines
Tandem Mass Tag labeling (TMT labels) based mass spectrometry was used to quantify lysine methylation from four different cell lines (n=4 replicates): MCF7 (ER positive breast cancer), MDAMB231 (TNBC), HCC1806 (TNBC), and MCF10A (non-cancerous), sans antibody enrichment. To boost the detection of ly...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-06-24 | MSV000095132 | MassIVE
ProteomicsKinome profiling of wild type and Ripk1 KO NIT-1 cells with or without proinflammatory cytokine stimulation
Type 1 diabetes (T1D) is characterized by autoimmune destruction of pancreatic β-cells, insulin insufficiency, and hyperglycemia. Receptor interacting protein kinase 1 (RIPK1) is a multifunctional regulator of cell fate with kinase and scaffolding functions. We previously identified RIPKs as regulat...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-10 | PXD068596 | Pride
Beta cells Kinase Inhibitor Bead Type 1 diabetes 
Sort   by:  
 Page size