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ProteomicsTIMP1 mediates astrocyte-dependent local immunosuppression in brain metastasis acting on infiltrating CD8+ T cells.
Immunotherapies against brain metastases have shown clinical benefits mainly when applied to locally asymptomatic patients. It is currently unclear why responses to this therapy drop in symptomatic brain metastases, since the use of corticoids is not consistently involved. We report here that a subp...
ORGANISM(S): Mus musculus (Mouse) 
2024-08-27 | PXD040436 | Pride
Microenvironment Brain metastasis Immunotherapy 
UnknownLong Range Endocrine Delivery of Circulating miR-210 to Endothelium Promotes Pulmonary Hypertension.
Not available
S-EPMC7429300 | biostudies-literature
UnknownFactors Associated with Heritable Pulmonary Arterial Hypertension Exert Convergent Actions on the miR-130/301-Vascular Matrix Feedback Loop.
Not available
S-EPMC6121519 | biostudies-literature
UnknownTIMP1 Mediates Astrocyte-Dependent Local Immunosuppression in Brain Metastasis Acting on Infiltrating CD8+ T Cells.
Not available
S-EPMC11726018 | biostudies-literature
GenomicsCyclin D1 ChIP-seq in H9 undifferentiated human pluripotent stem cells
H9 human pluripotent stem cells were grown in chemically defined media with Activin A and FGF2. Four 10cm plates with 70% confluency were used per sample. Cells were cross-linked by adding a final concentration of 1% PFA into culture media and incubated for 10 min at RT for Cyclin D1 ChIP. ChIP-seq ...
ORGANISM(S): Homo sapiens 
2016-02-01 | E-MTAB-3807 | biostudies-arrayexpress
UnknownUse of the Secreted Proteome of Trametes versicolor for Controlling the Cereal Pathogen Fusarium langsethiae.
Not available
S-EPMC6747115 | biostudies-literature
TranscriptomicsRNA-seq of WTAP knockdown human pluripotent stem cells during the exit from pluripotency induced by Activin/Nodal inhibition
This experiment was designed to monitor the gene expression changes induced by the knockdown of WTAP in human pluripotent stem cells (hPSCs) during the exit from pluripotency induced by the inhibition of Activin/Nodal signalling. hPSCs carrying a tetracycline-inducible short hairpin RNA (shRNA) agai...
ORGANISM(S): Homo sapiens 
2018-01-04 | E-MTAB-5230 | biostudies-arrayexpress
UnknownThe molecular rationale for therapeutic targeting of glutamine metabolism in pulmonary hypertension.
Not available
S-EPMC6625322 | biostudies-literature
UnknownExploring the phytoremediation potential of plant species in soils impacted by gold mining in Northern Colombia.
Not available
S-EPMC11835935 | biostudies-literature
UnknownTFEB controls sensitivity to chemotherapy and immuno-killing in non-small cell lung cancer.
Not available
S-EPMC11304671 | biostudies-literature
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