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ProteomicsPhosphoproteomic Effects of Acute Depletion of PP2A Regulatory Subunit Cdc55
Protein phosphatase regulatory subunits are increasingly recognized as promising drug targets. In the absence of an existing drug, inducible degradation provides a means of predicting candidate targets. We here employed auxin-inducible degradation of S. cerevisiae PP2A regulatory subunit Cdc55 in co...
ORGANISM(S): Saccharomyces Cerevisiae 
2021-01-27 | PXD019534 | panorama
ProteomicsPRM of Nth1 phospho-peptides in response to AGC-kinase inhibition
Protein phosphorylation cascades play a central role in the regulation of cell growth and protein kinases PKA, Sch9 and Ypk1 take centre stage in regulating this process in S. cerevisiae. To understand how these kinases co-ordinately regulate cellular functions we compared the phospho-proteome of ex...
ORGANISM(S): Saccharomyces Cerevisiae 
2020-03-22 | PXD015760 | panorama
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