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TranscriptomicsDendritic cell maturation by proinflammatory TNF or pathogenic Trypanosoma brucei antigens instruct similar T helper-2 cell responses in murine models of autoimmunity and asthma
Background Dendritic cells (DC) represent the major cell type leading to polarized T helper (Th) cell responses in vivo. The current data indicate that DC maturation under inflammatory conditions or by helminth infections induce only incomplete DC maturation bearing a partially tolerogenic potential...
ORGANISM(S): Mus musculus 
2012-03-19 | E-GEOD-28231 | biostudies-arrayexpress
TranscriptomicsBone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells
Self-renewing tissue-resident macrophages are thought to be exclusively derived from embryonic progenitors. However, whether circulating monocytes can also give rise to such macrophages has not been formally investigated. Here we use a new model of diphtheria toxin-mediated depletion of liver-reside...
ORGANISM(S): Mus musculus 
2015-11-21 | E-GEOD-75225 | biostudies-arrayexpress
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