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Acute effects of beta2-adrenergic receptor activation on macrophage transcriptome
Autophagy regulates glucagon secretion via the beta2-adrenergic pathway
The sympathetic nervous system (SNS) plays a central role in blood pressure regulation. Recent studies have shown that cells of the distal convoluted tubule (DCT) can be stimulated directly via the beta-adrenergic receptor resulting in activation of the NaCl cotransporter NCC. Whether these effects ...
ORGANISM(S): Mus musculus (Mouse) 
2021-05-17 | PXD019051 | Pride
Appropriate glucagon secretion from pancreatic alpha cells in response to hypoglycemia is an important component of maintaining glucose homeostasis. Dysregulated glucagon secretion leads to the delayed recovery from a hypoglycemic attack in type 1 diabetes patients which can be lethal. Although eluc...
ORGANISM(S): Homo sapiens 
2024-03-31 | GSE171352 | GEO
BackgroundSkeletal muscle is essential for metabolic health and physical function. While resistance training promotes muscle hypertrophy, alternative therapeutic strategies are needed for individuals unable to engage in physical activity. Because beta2-adrenergic stimulation induces muscle growth wi...
ORGANISM(S): Homo sapiens (Human) 
2026-01-26 | PXD064789 | Pride
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