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TranscriptomicsLoss of Foxp3-driven epigenetic modification leads to regulatory T cell insufficiency
Regulatory T cells (Tregs) are responsible for limiting autoimmunity and chronic inflammation. Foxp3 is a transcription factor that acts as a master regulator of Treg development and function. A serendipitous observation led to the realization that a well-characterized Foxp3gfp reporter mouse, whic...
ORGANISM(S): Mus musculus 
2012-12-07 | E-GEOD-35164 | biostudies-arrayexpress
TranscriptomicsPotentiation of regulatory T cell stability and function via a neuropilin-1:semaphorin-4a axis
Regulatory T cells (Treg) represent a critical immunoregulatory component of the immune system. The signals that maintain Treg stability and potentiate their function remain obscure. Here we show that the immune cell surface ligand semaphorin-4a (Sema4a) Sema treated and NRP1 knock outs were compare...
ORGANISM(S): Mus musculus 
2013-09-06 | E-GEOD-41185 | biostudies-arrayexpress
UnknownA second update on mapping the human genetic architecture of COVID-19.
Not available
S-EPMC10482689 | biostudies-literature
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