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TranscriptomicsmicroRNAseq of clear-cell renal cell carcinoma on surgical resection specimens of untreated primary tumors in humans
We aimed to assess differences in miRNA expression profiles in transcriptomic molecular subtypes of ccRCC (Beuselinck et al, Clinical Cancer Research 2015) and to correlate miRNAs with overal survival since diagnosis of ccRCC. Sequencing was done for 129 primary ccRCC (formalin-fixed paraffin-embe...
ORGANISM(S): Homo sapiens 
2020-07-22 | E-MTAB-9380 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of fresh frozen clear-cell renal cell carcinoma tissues treated with VEGFR-TKIs in first line
Transcriptomic analysis using qRT-PCR was performed on fresh frozen clear-cell renal cell carcinoma tissues treated with VEGFR-TKIs in first line (n=109). The transcriptomic data from this experiment were analyzed together with miRNA sequencing data from FFPE samples from the same tumor (E-MTAB-1058...
ORGANISM(S): Homo sapiens 
2021-06-07 | E-MTAB-10592 | biostudies-arrayexpress
TranscriptomicsMicroRNA sequencing of clear-cell renal cell carcinoma tissues (FFPE) treated with VEGFR-TKIs in first line.
We investigated tumoral miRNA expression of patients with clear-cell renal cell carcinoma treated with VEGFR-TKIs in first line. Sequencing was performed on 109 FFPE resection specimens. The samples were sequenced in 2 major batches (2014 and 2017).
ORGANISM(S): Homo sapiens 
2021-06-07 | E-MTAB-10586 | biostudies-arrayexpress
TranscriptomicsMethylation profiling by array of 108 clear cell renal cell carcinoma
A Cartes d'Identite des Tumeurs (CIT) project from the French Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net). Selecting patients with metastatic clear-cell renal cell carcinoma (m-ccRCC) who might benefit from treatment wi...
ORGANISM(S): Homo sapiens 
2016-02-26 | E-MTAB-3274 | biostudies-arrayexpress
TranscriptomicsGenotyping by array of 108 clear cell renal cell carcinoma
A Cartes d'Identite des Tumeurs (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net); Selecting patients with metastatic clear-cell renal cell carcinoma (m-ccRCC) who might benefit from treatment with targeted tyrosine kinase inhibitors (TKIs) is a challenge. ...
ORGANISM(S): Homo sapiens 
2015-01-27 | E-MTAB-3269 | biostudies-arrayexpress
TranscriptomicsExpression Profiling of Clear cell renal carcinoma
Selecting patients with metastatic clear-cell renal cell carcinoma (m-ccRCC) who might benefit from treatment with targeted tyrosine kinase inhibitors (TKIs) is a challenge. Our aim was to identify molecular markers associated with outcome in m-ccRCC patients treated with sunitinib. A Cartes d’Ident...
ORGANISM(S): Homo sapiens 
2015-01-27 | E-MTAB-3267 | biostudies-arrayexpress
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