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UnknownPhysicochemical properties and angiotensin-I converting enzyme inhibitory activity of lipid-free ribbon fish (Lepturacanthus savala) protein hydrolysate.
Not available
S-EPMC9813303 | biostudies-literature
GenomicsChIP-seq of CTCF, RAD21, and TOP2B binding sites in three human tissue samples with hepatocellular carcinoma
The roles of topoisomerases in somatic mutagenesis in cancer are poorly understood and their DNA-binding landscape remains largely unmapped. Here we generated genome-wide DNA-binding maps of TOP2B, CTCF, and RAD21 in human hepatocellular carcinoma samples.
ORGANISM(S): Homo sapiens 
2024-02-01 | E-MTAB-13301 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human mammary epithelial cell line MCF10A with RMRP/CCDC107/ARHGEF39-targeted CRISPR edits vs. scramble controls
The purpose of these experiments was to validate the role of a frequently mutated regulatory element bound by TOP2B using a functional genomics approach. Specifically, CRISPR/Cas9 was employed to selectively target the promoter of RMRP and non-coding regions of CCDC107 and ARHGEF39.
ORGANISM(S): Homo sapiens 
2025-01-01 | E-MTAB-14611 | biostudies-arrayexpress
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