Sort   by:  
 Page size 
TranscriptomicsThe multifaceted balance of TNF-a and type I / II interferon responses in SLE and RA: how monocytes manage the impact of cytokines
Many cytokines are involved in the pathogenesis of autoimmune diseases and are recognized as relevant therapeutic targets to attenuate inflammation, such as TNFα in RA and IFNα/γ in SLE. To relate the transcriptional imprinting of cytokines in a cell type-specific and disease-specific manner, we gen...
ORGANISM(S): Homo sapiens 
2012-06-13 | E-GEOD-38351 | biostudies-arrayexpress
TranscriptomicsT helper lymphocyte- and monocyte-specific type I interferon (IFN) signatures in autoimmunity and viral infection.
This study demonstrates quantitative and qualitative differences between type I IFN signatures in autoimmunity and viral infection using purified CD4pos T cells and CD16pos- and CD16neg-monocyte subsets. We were able to discriminate between cell-specific viral response signatures and the pathogenica...
ORGANISM(S): Homo sapiens 
2014-01-06 | E-GEOD-51997 | biostudies-arrayexpress
Sort   by:  
 Page size