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To identify receptors and pathways active in glioblastoma (GBM) stem like cells (GSCs), we generated and screened thousands of monoclonal antibodies (mAbs) for preferential binding to primary cultures enriched in GSCs. This led to the identification of the integrin alpha 7 (ITGA7) as a major laminin...
ORGANISM(S): Homo sapiens (Human) 
2018-01-10 | PXD006069 | Pride
Apoptosis and autophagy are programs of controlled cellular suicide or survival, closely interconnected at multiple levels to ensure balanced answers to stress signals, and often dysregulated in cancer. Here, we identified FYCO1, a protein that promotes microtubule plus end–directed transport of aut...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD033760 | Pride
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