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Transcriptome analysis was performed from human U87 glioblastoma cell clones: U87 IRE1.NCK DN (U87dn, IRE1 dominant negative) and U87 control (U87ctrl, empty plasmid). Cells were grown in DMEM supplemented with 10% FBS and glutamine for 16 hours in culture prior mRNA isolation and analyses U87dn c...
ORGANISM(S): Homo sapiens 
Modern functional genomic approaches may help to better understand the molecular events involved in tissue morphogenesis and to identify molecular signatures and pathways. We have recently applied transcriptomic profiling to evidence molecular signatures in the development of the normal chicken chor...
ORGANISM(S): Gallus gallus 
In order to discover molecular pathways and players in renal cancer development and metastasis, we developed a mouse model to generate sequentially more aggressive and specialized cell lines. Multiple cell lines for primary tumor growth, survival in the blood circulation and lung metastasis or metas...
ORGANISM(S): Mus musculus 
Murine renal carcinoma RENCA cells were injected in BALB/c mice to generated either primary tumours (orthotopically) or lunge metastases (through tail vein injection, or directly forming from primary tumors). Samples were snap-frozen and processed for single nucleus isolation and RNA seq analysis. T...
ORGANISM(S): Mus musculus 
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