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GenomicsTo examine the role of p300 in the SMARCA4–p53 regulatory axis, we performed ChIP-seq to assess p300, p53, H3K27ac, HDAC1, HDAC2 occupancy in BIN-67 cells
ChIP-seq was performed in BIN-67, BIN-67 p53ko, BIN-67 with SMARCA4 restoration and BIN-67 p53ko cells with SMARCA4 restoration to assess the impact of SMARCA4 and p53 on the pull downs of p300, H3K27ac, p53, HDAC1 and HDAC2.
ORGANISM(S): Homo sapiens 
2026-05-05 | E-MTAB-15700 | biostudies-arrayexpress
GenomicsAssessing SMARCA4 restoration contribution to global changes in p300 occupancy in BIN-67 cells
We aim to test how SMARCA4 restoration impacts p300 occupancy distribution. To this aim we generated ChIP-seq samples in BIN-67 with or without A-485 treatment (1 μM, 24h), as a proxy for p300 acetylatransferase inhibition, and BIN-67 with inducible SMARCA4 restoration (1 μg/ml Doxycycline for 24h)....
ORGANISM(S): Homo sapiens 
2026-05-05 | E-MTAB-15699 | biostudies-arrayexpress
TranscriptomicsTranscription analysis of the porcine alveolar macrophage M-oM-
Investigation of whole genome gene expression level changes in porcine alveolar macrophage response to co-infection of PRRSV and M. hyopneumoniae The results in this study will be further described in Bin li et al., 2013. BMC genomics. A 24 chip study using total RNA recovered from four separate gro...
ORGANISM(S): Sus scrofa 
2014-05-30 | E-GEOD-49882 | biostudies-arrayexpress
TranscriptomicsRNA-seq from ENCODE/UW
This data was generated by ENCODE. If you have questions about the data, contact the submitting laboratory directly (Richard Sandstrom mailto:sull@u.washington.edu). If you have questions about the Genome Browser track associated with this data, contact ENCODE (mailto:genome@soe.ucsc.edu). This tra...
ORGANISM(S): Mus musculus 
2012-07-20 | E-GEOD-39524 | biostudies-arrayexpress
Transcriptomicsp53-ko rescues gene expression changes mediated by p300 acetyltransferase inhibition
RNA-seq samples in BIN-67 and BIN-67p53-ko cells with or without A-485 treatment (1μM, 24h). The goal of the experiment is to assess the genes that are regulated by p300 acetyltransferase inhibition using A-485 treatment and weather p53-ko can rescue this phenotype.
ORGANISM(S): Homo sapiens 
2026-05-05 | E-MTAB-15706 | biostudies-arrayexpress
UnknownOptimizing e-commerce warehousing through open dimension management in a three-dimensional bin packing system.
Not available
S-EPMC10588690 | biostudies-literature
GenomicsChIP-seq of Tcfap2c in Neu mammary cancer cells
Tumors were harvested from mice carrying the rat activated Neu-oncogene and made into a single cell suspension. ChIP-SEQ was carried out as previously described in Kulak MV, Cyr AR, Woodfield GW, Bogachek M, Spanheimer PM, Li T et al. Transcriptional regulation of the GPX1 gene by TFAP2C and aberran...
ORGANISM(S): Mus musculus 
2015-04-01 | E-GEOD-61394 | biostudies-arrayexpress
GenomicsOpen Chromatin by FAIRE from ENCODE/OpenChrom(UNC Chapel Hill)
This data was generated by ENCODE. If you have questions about the data, contact the submitting laboratory directly (Terry Furey mailto:tsfurey@duke.edu). If you have questions about the Genome Browser track associated with this data, contact ENCODE (mailto:genome@soe.ucsc.edu). These tracks displa...
ORGANISM(S): Homo sapiens 
2012-01-24 | E-GEOD-35239 | biostudies-arrayexpress
TranscriptomicsExamining the effect of SMARCA4–p53 regulatory axis on SCCOHT cells transcription
To examine the role SMARCA4-p53 regulatory axis in SCCOHT cells we performed RNA-seq in BIN-67 cells with SMARCA4 restoration, p53ko alone or combined with SMARCA4 and idasanutlin treatment (0.5μM, 24h) which increase the stability of p53 and its protein levels in SCCOHT.
ORGANISM(S): Homo sapiens 
2026-05-05 | E-MTAB-15707 | biostudies-arrayexpress
UnknownA new bin size index method for statistical analysis of multimodal datasets from materials characterization.
Not available
S-EPMC10322845 | biostudies-literature
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