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MetabolomicsSacha inchi oil alleviates gut microbiota dysbiosis and improves hepatic lipid dysmetabolism in high-fat diet-fed rats
Dietary ω-3 polyunsaturated fatty acids (PUFAs) are beneficial for humans against the development of hyperlipidaemia, but the underlying mechanisms are still poorly understood. Here, we demonstrated that oral consumption of sacha inchi oil, which is rich in α-linolenic acid, alleviated dyslipidemia,...
2022-02-21 | MTBLS1225 | MetaboLights
UnknownDimethyloxalylglycine prevents bone loss in ovariectomized C57BL/6J mice through enhanced angiogenesis and osteogenesis.
Not available
S-EPMC4231053 | biostudies-literature
ProteomicsIntegrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer
Explore This Study at the NCI Proteomic Data Commons

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-08-28 | MSV000084246 | MassIVE
MetabolomicsSerum metabolomics analysis of patients with chronic obstructive pulmonary disease and 'frequent exacerbator' phenotype

BACKGROUND: Chronic obstructive pulmonary disease (COPD) exacerbations significantly contribute to morbidity and mortality. The complex nature of COPD presents challenges in accurately predicting and understanding frequent exacerbations.

OBJECTIVE: This stu...

2024-02-23 | MTBLS9119 | MetaboLights
ProteomicsCPTAC CCRCC Discovery Study - DIA Proteome
This is a supplementary study to the CPTAC CCRCC Discovery Study - Proteome. Unlabeled, digested peptide material from individual tissue samples (ccRCC and NAT) was spiked with index Retention Time (iRT) peptides (Biognosys) and subjected to data-independent acquisition (DIA) analysis. Kidney cance...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-10-04 | MSV000093041 | MassIVE
TranscriptomicsMicroRNA profiling of mouse embryonic stem cells during retinoic acid-induced differentiation
Changes in microRNA expression profile during retinoic acid-induced differentiation of mouse embryonic stem cells.
ORGANISM(S): Mus musculus 
2007-04-01 | E-MEXP-977 | biostudies-arrayexpress
TranscriptomicsReprogramming fibroblasts into bi-potential hepatic stem cells by defined factors
Recent studies have demonstrated direct reprogramming of fibroblasts into a range of somatic cell types, but to date stem/progenitor cells have only been reprogrammed for the blood and neuronal lineages. We previously reported generation of induced hepatocyte-like (iHep) cells by transduction of Gat...
ORGANISM(S): Mus musculus 
2013-07-19 | E-GEOD-48486 | biostudies-arrayexpress
TranscriptomicsATF4 governs functional expansion of hematopoietic stem cells partially via Angptl3 in the fetal liver microenvironment (RNA-Seq)
In this study, we demonstrated that deletion of the activating transcription factor 4 (ATF4) resulted in severely impaired HSC expansion in the fetal liver at E12.5 and E15.5. In contrast, generation of the first HSC population in the aorta-gonad-mesonephros region at E11.5 was not significantly aff...
ORGANISM(S): Mus musculus 
2015-11-20 | E-GEOD-66380 | biostudies-arrayexpress
TranscriptomicsATF4 governs functional expansion of hematopoietic stem cells partially via Angptl3 in the fetal liver microenvironment (array)
In this study, we demonstrated that deletion of the activating transcription factor 4 (ATF4) resulted in severely impaired HSC expansion in the fetal liver at E12.5 and E15.5. In contrast, generation of the first HSC population in the aorta-gonad-mesonephros region at E11.5 was not significantly aff...
ORGANISM(S): Mus musculus 
2015-11-20 | E-GEOD-66381 | biostudies-arrayexpress
ProteomicsLC-MS proteomic profiling of trace FFPE samples in gastrointestinal cancer
Proteomic profiling of forty trace samples (20 duodenum cancer samples and 20 gastric cancer samples).
ORGANISM(S): Homo Sapiens 
2021-06-16 | PXD026756 |
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