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MetabolomicsAntimicrobial Efficacy of Bifidobacterium longum FB1-4 Cell-Free Supernatant Against MRSA: Insights into Mechanisms and Food Matrix Application

The food safety landscape faces a significant challenge from methicillin-resistant Staphylococcus aureus (MRSA), a virulent and antibiotic-resistant foodborne pathogen. This study investigates the antimicrobial properties and mechanisms of cell-free supernatant (CFS) from Bifidobacterium longum F...

2026-02-26 | MTBLS13481 | MetaboLights
TranscriptomicsBiofilm matrix regulation by Candida albicans Zap1
The Zap1 ChIP-chips were performed in a/alpha cell types using C-terminally Myc-tagged proteins and Myc antibodies. ChIPs were performed on 48 hour biofilm cells grown in Spider medium. Two biological replicates were performed, and normalized data is reported in matrix. Myc tagged strains were comp...
ORGANISM(S): Candida albicans 
2011-06-09 | E-GEOD-29785 | biostudies-arrayexpress
ProteomicsP.aeruginosa - Whole organism, Biofilm, SC (Toyofuku,j_proteome_res,2012)
abundance based on Spectral counting, biofilm, Interaction consistency score: 7.2, Coverage: 31
ORGANISM(S): 208964 
2012-00-00 | 1231515390 | PAXDB
ProteomicsBiofilm matrix regulation by Candida glabrata Zap1 under acidic conditions: transcriptomic and proteomic analyses
The vaginal acidic environment potentiates the formation of Candida glabrata biofilms, leading to complicated and recurrent infections. Importantly, the regulation of biofilm matrix is known to contribute to the recalcitrant features of Candida biofilms. In this study we reveal a new matrix regulato...
ORGANISM(S): Candida glabrata (Yeast) (Torulopsis glabrata) 
2024-10-28 | PXD044153 | Pride
Candida spp. Transcriptome Zap1 targets Acidic environment Proteome Biofilm matrix 
TranscriptomicsFunctional genomic profiling of Aspergillus fumigatus biofilm reveals enhanced production of the mycotoxin gliotoxin
The opportunistic pathogenic mold Aspergillus fumigatus is an increasing cause of morbidity and mortality in immunocompromised and, in part, immunocompetent patients. Like bacteria or yeast, A. fumigatus can grow in multicellular communities by the formation of a hyphal network encased in an extrace...
ORGANISM(S): Aspergillus fumigatus 
2010-07-01 | E-GEOD-19430 | biostudies-arrayexpress
MetabolomicsEnhanced fatty acid synthesis by Sigma28 in stringent responses contributes to multidrug resistance and biofilm formation in Helicobacter pylori

The metabolism of bacteria is closely associated with antibiotic resistance, yet the role of metabolism in the resistance of Helicobacter pylori remains unclear. In this study, we conducted integrated analysis using transcriptomics and non-targeted metabolomics to investigate the metabolic change...

2024-06-26 | MTBLS9981 | MetaboLights
ProteomicsProtein composition of the biofilm matrix and the outer membrane vesicles (OMVs) during iron-sufficient and iron-restricted growth.
There is limited efficacy in vaccines currently available to prevent some animal diseases of bacterial origin, such as bovine respiratory disease due to Histophilus somni. Protective efficacy can potentially be improved if bacterial antigens expressed in the host are included in vaccines. During H. ...
ORGANISM(S): Bos taurus (Bovine) 
2025-05-15 | PXD061987 | Pride
Histophilus somni Iron acquisition Outer membrane vesicles Protective antigen Reverse vaccinology Biofilm matrix 
TranscriptomicsExtracellular Matrix Formation Enhances the Ability of Streptococcus pneumoniae to Cause Invasive Disease
Background. During infection, pneumococci exist mainly in sessile biofilms rather than in planktonic form, except during sepsis. However, relatively little is known about how biofilms contribute to pneumococcal pathogenesis. Methods. We performed a biofilm assay and mouse infection experiments on op...
ORGANISM(S): Streptococcus pneumoniae 
2011-04-20 | E-BUGS-117 | biostudies-arrayexpress
ProteomicsCoordination of fungal biofilm development by extracellular vesicle cargo
The fungal pathogen Candida albicans can form biofilms that protect it from drugs and the immune system. The biofilm cells release extracellular vesicles (EVs) that promote extracellular matrix formation and resistance to antifungal drugs. Here, we define functions for numerous EV cargo proteins in ...
ORGANISM(S): Candida albicans (Yeast) 
2022-02-16 | PXD028596 | Pride
Candida albicans Extracellular vesicles Matrix proteomics Biofilm Biofilms 
TranscriptomicsBile-induced biofilm formation in Bacteroides thetaiotaomicron requires magnesium efflux by an RND pump
The study is about the role of Bacteroides thetaiotaomicron in the human gut microbiota, specifically its ability to form biofilms in response to bile salts. The study found that bile induces the expression of certain efflux pumps, and inhibiting these pumps impairs biofilm formation. Among the indu...
ORGANISM(S): Bacteroides thetaiotaomicron 
2024-03-19 | E-MTAB-13460 | biostudies-arrayexpress
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