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In this project, we investigated the effets of heat inactivation for different time points to evaluate the biosafety and proteome changes.
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2022-06-09 | PXD027011 | Pride
Biosafety circuits for Mycoplasma - DNA-seq for passages 2, 3 and 15 of clonal Mycoplasma pneumoniae biosafety strains to study long-term stability of kill-switch devices
We have engineered synthetic gene switches to control and limit Mycoplasma growth for biosafety containment applications. Mycoplasmas have high mutation rates and, the accumulation of mutations that inactivate the circuit is expected. However, the question is how resilient is the kill-switch to muta...
ORGANISM(S): Mycoplasma pneumoniae M129 
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