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The alternative sigma factor M-OM-^CB of Staphylococcus aureus is involved in the coordination of the general stress response, expression of virulence determinants and modulation of antibiotic resistance levels. It controls a large regulon, either directly by recognizing conserved M-OM-^CB promoter ...
ORGANISM(S): Staphylococcus aureus 

Medulloblastomas (MBs) are malignant pediatric brain tumors that are molecularly and clinically very heterogenous. The application of omics technologies - mainly studying nucleic acids - has significantly improved MB classification and stratification, but treatment options are still unsatisfactor...

2024-05-30 | MTBLS9830 | MetaboLights
Dosage compensation in D. melanogaster males is achieved via targeting of the MSL complex to X chromosomal genes. This is proposed to involve initial sequence-specific recognition of the X at ~150-300 chromatin entry sites, and subsequent spreading to nearby active genes. Here we test a model in whi...
ORGANISM(S): Drosophila melanogaster 
This study provides critical insights into the adverse effects of titanium dioxide (E171) on human gastrointestinal health and its potential molecular mechanisms of action, marking a significant advancement in food toxicology. Through a human dietary intervention study involving 31 participants cons...
ORGANISM(S): Homo sapiens 
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