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GenomicsBispecific dendritic-T Cell Engager potentiates anti-tumor immunity
Bispecific dendritic-T Cell Engager potentiates anti-tumor immunity
PRJNA1048445 | ENA
UnknownAntitumor activity of T cells secreting αCD133-αCD3 bispecific T-cell engager against cholangiocarcinoma.
Not available
S-EPMC8936442 | biostudies-literature
GenomicsEarly cytokine and chemokine signals shape the anti-AML activity of bispecific engager-secreting T cells
Early cytokine and chemokine signals shape the anti-AML activity of bispecific engager-secreting T cells
PRJNA1160783 | ENA
UnknownThe landscape of bispecific T cell engager in cancer treatment.
Not available
S-EPMC8157659 | biostudies-literature
TranscriptomicsBispecific dendritic-T Cell Engager potentiates anti-tumor immunity
Immune checkpoint inhibition treatment using aPD-1 monoclonal antibodies is a promising cancer immunotherapy approach. However, its effect on tumor immunity is narrow, as most patients do not respond to the treatment or suffer from recurrence. We show that the crosstalk between conventional type I d...
ORGANISM(S): Mus musculus 
2024-02-06 | GSE249283 | GEO
UnknownTherapeutic bispecific T-cell engager antibody targeting the intracellular oncoprotein WT1.
Not available
S-EPMC4600043 | biostudies-literature
GenomicsEvolution of T-Cell Fitness through AML Progression: Enhanced Bispecific T-Cell Engager-mediated Function of Bone Marrow T Cells at Remission Compared to Initial Diagnosis and Relapse [transcriptome analysis]
Evolution of T-Cell Fitness through AML Progression: Enhanced Bispecific T-Cell Engager-mediated Function of Bone Marrow T Cells at Remission Compared to Initial Diagnosis and Relapse [transcriptome analysis]
PRJNA1084807 | ENA
GenomicsEvolution of T-Cell Fitness through AML Progression: Enhanced Bispecific T-Cell Engager-mediated Function of Bone Marrow T Cells at Remission Compared to Initial Diagnosis and Relapse [epigenome analysis]
Evolution of T-Cell Fitness through AML Progression: Enhanced Bispecific T-Cell Engager-mediated Function of Bone Marrow T Cells at Remission Compared to Initial Diagnosis and Relapse [epigenome analysis]
PRJNA1084808 | ENA
UnknownNeural stem cells secreting bispecific T cell engager to induce selective antiglioma activity.
Not available
S-EPMC7936285 | biostudies-literature
UnknownBispecific NK-cell engager targeting BCMA elicits stronger antitumor effects and produces less proinflammatory cytokines than T-cell engager.
Not available
S-EPMC10126364 | biostudies-literature
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