Sort   by:  
 Page size 
ProteomicsAncient origin and dynamic evolution of bivalent spider toxins
Bivalent peptide toxins comprising two cysteine-rich domains have evolved from single-domain precursors on multiple occasions in animal venoms, resulting in enhanced molecular target selectivity and avidity. Although bivalent toxins are emerging as prevalent in animal venoms, the genomic and evoluti...
ORGANISM(S): Lasiodora parahybana Fufius Hadronyche cerberea Chaetopelma olivaceum Cyrtocarenum grajum Brachypelma boehmei Avicularia avicularia Chilobrachys Harpactira 
2026-06-08 | PXD070138 | Pride
Australian funnel-web spider Inhibitor cystine knot Pi-hexatoxin Hi1a Spider venom Bivalent peptides Mygalomorphae 
UnknownDiscovery of Supra-Bivalent GSK3β Inhibitory Peptides Containing an ATP-Mimetic Amino Acid.
Not available
S-EPMC12814355 | biostudies-literature
ProteomicsEBS is a bivalent histone reader that regulates floral phase transition in Arabidopsis
The ability of cells to perceive and translate versatile cues into differential chromatin and transcriptional states is critical for many biological processes1-4. In plants, timely transition to a flowering state is crucial for successful reproduction5-7. EARLY BOLTING IN SHORT DAY (EBS) is a negati...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-09-09 | PXD009794 | Pride
Histone Arabidopsis Chromatin 
UnknownBivalent peptides as PDZ domain ligands.
Not available
S-EPMC2169291 | biostudies-literature
UnknownDesign and Synthesis of Potent Bivalent Peptide Agonists Targeting the EphA2 Receptor.
Not available
S-EPMC3807576 | biostudies-literature
UnknownCaspase-3-Responsive, Fluorogenic Bivalent Bottlebrush Polymers.
Not available
S-EPMC12323701 | biostudies-literature
UnknownGAS41 Recognizes Diacetylated Histone H3 through a Bivalent Binding Mode.
Not available
S-EPMC6611172 | biostudies-literature
ProteomicsHomo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation
E3 ubiquitin ligases are key enzymes within the ubiquitin proteasome system which catalyze the ubiquitination of proteins, targeting them for proteasomal degradation. E3 ligases are gaining importance as targets to small molecules, both for direct inhibition and to be hijacked to induce the degradat...
ORGANISM(S): Homo sapiens (Human) 
2018-10-24 | PXD007594 | Pride
E3 ligases  protacs  von hippel-lindau protein  protein degradation  chemical dimerizers. 
UnknownDesign of a True Bivalent Ligand with Picomolar Binding Affinity for a G Protein-Coupled Receptor Homodimer.
Not available
S-EPMC9366271 | biostudies-literature
UnknownOne-step (18)F labeling of non-peptidic bivalent integrin αvβ3 antagonist for cancer imaging.
Not available
S-EPMC4334273 | biostudies-literature
Sort   by:  
 Page size