Bix-01294 - OmicsDI

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ProGenTomics, Laboratory of Pharmaceutical Biotechnology, Ghent University, B-9000 Ghent, Belgium (1)

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SMYD2 specificly regulate BIX-01294 induced TP53 target genes revealed by RNA-Seq

We characterized expression profilings of SMYD2 knockdown and control cells treated by BIX-01294 and Rapamycin. We used siRNAs to knockdown SMYD2 in HCT116 cells, and NC as control. We treated those cell lines with BIX-01294 and Rapamycin, and the expression profilings were perfomed by Illumina high...

ORGANISM(S): Homo sapiens

2015-01-01 | E-GEOD-61255 | biostudies-arrayexpress

The G9a histone methyltransferase inhibitor BIX-01294 modulates gene expression during gametocyte development and transmission

PRJNA560931 | ENA

SMYD2 specificly regulate BIX-01294 induced TP53 target genes revealed by RNA-Seq

We characterized expression profilings of SMYD2 knockdown and control cells treated by BIX-01294 and Rapamycin.

ORGANISM(S): Homo sapiens

2015-01-01 | GSE61255 | GEO

The G9a histone methyltransferase inhibitor BIX-01294 modulates gene expression during gametocyte development and transmission

Transmission of the malaria parasite Plasmodium falciparum from the human to the mosquito is initiated by sexual precursor cells, the gametocytes. Gametocytes are formed in response to stress signals and following up-take by a blood-feeding Anopheles mosquito initiate sexual reproduction. Gametocyte...

ORGANISM(S): Plasmodium falciparum

2019-11-25 | GSE136008 | GEO

Effect of BIX-01294 on H3K9me2 levels and the imprinted gene Snrpn in mouse embryonic fibroblast cells.

Not available

S-EPMC4613706 | biostudies-literature

EHMT2 inhibitor BIX-01294 induces endoplasmic reticulum stress mediated apoptosis and autophagy in diffuse large B-cell lymphoma cells.

Not available

S-EPMC7797660 | biostudies-literature

The selective activation of p53 target genes regulated by SMYD2 in BIX-01294 induced autophagy-related cell death.

Not available

S-EPMC4285553 | biostudies-literature

Inhibition of Histone H3K9 Methylation by BIX-01294 Promotes Stress-Induced Microspore Totipotency and Enhances Embryogenesis Initiation.