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TranscriptomicsRibosome profiling with MN and RNaseI
The aim of this experiment is to compare nucleases used in ribosome profiling using Drosophila melanogaster Kc167 cells and human U2OS osteosarcoma cells. Ribosome profiling was performed from nuclease digested samples using sucrose cushion centrifugation separated ribosomes.
ORGANISM(S): Homo sapiens 
2015-01-08 | E-MTAB-2421 | biostudies-arrayexpress
TranscriptomicsScaling of gene expression with liver cell size in vivo
A partially hepatectomized mouse liver with a liver-specific conditional Cdk1 knock-out genotype grows back to the normal size in the absence of cell divisions resulting in highly enlarged nuclear and cell size. This experiment analyses gene expression in four sets of mouse livers all with different...
ORGANISM(S): Mus musculus 
2014-03-06 | E-MTAB-1297 | biostudies-arrayexpress
TranscriptomicsAnalysis of conditions leading to 3'UTR ribosome protected footprints
Ribosome profiling data from U2OS, HeLa and Kc167 cells under various lysis conditions and using immunoprecipitation to purifiy ribosome associated footprints. Two human cell lines (U2OS and HeLa cells) and a Drosophila melanogaster cell line (Kc167) are used to see if the 3'UTR reads are identified...
ORGANISM(S): Homo sapiens 
2015-01-08 | E-MTAB-3135 | biostudies-arrayexpress
TranscriptomicsCell size gene expression in Drosophila Kc167 cells
The aim of this experiment is to shed light on mechanisms related to cell size homeostasis. Gene expression changes after RNAi mediated perturbations of cell size are analysed.
ORGANISM(S): Drosophila melanogaster 
2015-02-24 | E-MTAB-2651 | biostudies-arrayexpress
ProteomicsMIRO-1 interacts with VDAC-1 to regulate mitochondrial membrane potential in Caenorhabditis elegans
Precise regulation of mitochondrial fusion and fission is essential for cellular activity and animal development. Imbalances between these processes can lead to fragmentation and loss of normal membrane potential in individual mitochondria. In this study, we show that MIRO-1 is stochastically elevat...
ORGANISM(S): Caenorhabditis Elegans 
2023-05-10 | PXD040748 |
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