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TranscriptomicsDifferential production of Type I IFN determines the reciprocal levels of IL-10 and proinflammatory cytokines produced by C57BL/6 and BALB/c macrophages
Pattern recognition receptors (PRR) detect microbial products and induce cytokines which shape the immunological response. Interleukin-12 (IL-12), tumor necrosis factor alpha (TNF-α) and IL-1β are proinflammatory cytokines which can be essential for resistance against infection, but if produced at...
ORGANISM(S): Mus musculus 
2016-09-07 | E-GEOD-79809 | biostudies-arrayexpress
UnknownImplementation of a Statewide Fentanyl Possession Law and Opioid-Related Overdose Deaths.
Not available
S-EPMC12317351 | biostudies-literature
TranscriptomicsTranscription profiling of blackcurrant (Ribes nigrum cv Ben Hope) bud tissue during dormancy and bud-break.
Transcriptional analysis of staged leaf bud tissue during dormancy and bud-break in blackcurrant using SCRI custom Ribes 4k arrays
ORGANISM(S): Ribes nigrum 
2010-05-01 | E-TABM-807 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse triplicate samples of RAW 264.7 murine macrophages either untreated, stimulated with 100 ng/ml LPS for 18 hours, or constituitively over-expressing CstF-64
Triplicate samples of RAW 264.7 murine macrophages either untreated, stimulated with 100 ng/ml LPS for 18 hours, or constituitively over-expressing CstF-64 were analyzed by microarray using Affymetrix murine gene chip 430A.
ORGANISM(S): Mus musculus 
2007-11-06 | E-GEOD-2002 | biostudies-arrayexpress
TranscriptomicsModulation of colonic inflammation in Mdr1a-/- mice by green tea polyphenols and their effects on the colon transcriptome and proteome
This study tested the anti-inflammatory potential of a green tea extract rich in polyphenols (GrTP) in the colon of the multi-drug resistance targeted mutation (Mdr1a-/-) mouse model of IBD. A colonic histological injury score was determined for each mouse to establish the effect of GrTP on inflamma...
ORGANISM(S): Mus musculus 
2012-10-18 | E-GEOD-41644 | biostudies-arrayexpress
UnknownImplications of the 2019-2020 megafires for the biogeography and conservation of Australian vegetation.
Not available
S-EPMC7884386 | biostudies-literature
MetabolomicsProMetIS, deep phenotyping of mouse models by combined proteomics and metabolomics analysis

Genes are pleiotropic and getting a better knowledge of their function requires a comprehensive characterization of their mutants. Here, we generated multi-level data combining phenomic, proteomic and metabolomic acquisitions from plasma and liver tissues of two C57BL/6 N mouse models lacking the...

2021-09-01 | MTBLS1903 | MetaboLights
TranscriptomicsDiscovery and validation of a novel expression signature for recurrence in high-risk bladder cancer post-cystectomy
Purpose: Selecting muscle-invasive bladder cancer patients for adjuvant therapy is currently based on clinical variables with limited power. We hypothesized that genomic-based signatures can outperform clinical models to identify patients at higher risk. Method:Transcriptome-wide expression profiles...
ORGANISM(S): Homo sapiens 
2014-10-27 | E-GEOD-57933 | biostudies-arrayexpress
TranscriptomicsGene profiling of HSCs in C57BL/6 TEL-SYK BM versus control
The aim of the study was to analyse gene expression differences in LT and ST HSCs in BM of TEL-SYK transplanted versus control C57BL/6mice
ORGANISM(S): Mus musculus 
2014-12-31 | E-MTAB-2240 | biostudies-arrayexpress
ProteomicsInhibition of the mitochondrial disulfide relay system impairs liver cancer cell proliferation
Augmenter of liver regeneration (ALR) is a critical multi-isoform protein with its longer isoform, located in the mitochondrial intermembrane space, being part of the mitochondrial disulfide relay system (DRS). Upregulation of ALR was observed in multiple forms of cancer, among them hepatocellular c...
ORGANISM(S): Rattus rattus (Black rat) 
2022-02-17 | PXD026695 | Pride
Mitochondria Heme Hcc Disulfide relay Iron 
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