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ProteomicsIntegrated tissue and urinary proteomic analysis of prostate cancer and MRI visibility
This study aimed to explore proteomic alterations associated with prostate cancer presence, aggressiveness, and MRI visibility. Tissue and preoperative urine samples were collected from patients diagnosed with benign prostatic hyperplasia, indolent prostate cancer, and clinically significant prostat...
ORGANISM(S): Homo sapiens (Human) 
2026-04-06 | PXD074635 | Pride
Prostate cancer  proteomics  urin  tissue  mass spectrometry Dia  biomarker discovery 
TranscriptomicsAnalysis of the melon (Cucumis melo) small RNAome by high-throughput pyrosequencing
Melon (Cucumis melo L.) is a commercially important fruit crop that is cultivated worldwide. The melon research community has recently benefited from the determination of a complete draft genome sequence and the development of associated genomic tools, which have allowed us to focus on small RNAs (s...
ORGANISM(S): Cucumis melo 
2011-08-03 | E-GEOD-28653 | biostudies-arrayexpress
TranscriptomicsExpression data from MALD1 and MCL cases
Patients with conventional mantle cell lymphoma (MCL) show an aggressive clinical behavior. However, cases fulfilling the WHO criteria for MCL, but that remain asymptomatic without treatment, have been reported. In an attempt to understand this heterogeneity, we have compared 17 typical cases of MCL...
ORGANISM(S): Homo sapiens 
2013-12-23 | E-GEOD-45717 | biostudies-arrayexpress
TranscriptomicsMiRNA expression in adipose tissue and liver from a spontaneous rat model of Type 2 diabetes
MicroRNAs (miRNAs) are non-coding RNA molecules involved in post-transcriptional control of gene expression of a wide number of genes, including those involved in glucose homeostasis. Type 2 diabetes (T2D) is characterized by hyperglycaemia and defects in insulin secretion and action at target tissu...
ORGANISM(S): Rattus norvegicus 
2010-05-16 | E-GEOD-17058 | biostudies-arrayexpress
TranscriptomicsExpression data from rice leaves treated or not with fungal elicitors and high-throughput pyrosequencing of endogenous small RNAs from Oryza sativa
High-throughput sequencing of small RNAs from rice was used to identify distinct miRNAs that are responsive to elicitors from the fungal pathogen Magnaporthe oryzae. [Expression profiling by array] We used microarrays to determine the expression behaviour of target genes for elicitor-regulated miRN...
ORGANISM(S): Oryza sativa Japonica Group 
2014-01-15 | E-GEOD-30583 | biostudies-arrayexpress
Genomicsena-DATASET-Hospital Clinic Barcelona-21-07-2015-12:09:53:274-78 - samples
RNASeq sequencing. Each library was sequenced using TruSeq SBS Kit v3-HS, in paired-end mode with a read length of 2 × 76 bp. We generated more than 20 million paired-end reads for each sample in a fraction of a sequencing lane on HiSeq2000 (Illumina Inc.) following the manufacturer’s protoc...
EGAD00001001443 | EGA
GenomicsIntegrated Genomic Analysis of Chronic Lymphocytic Leukaemia
Chronic lymphocytic leukaemia (CLL) is a frequent and heterogeneous disease whose genetic alterations determining the clinicobiological behaviour are not fully understood. Here, we describe a comprehensive evaluation of the genomic landscape of 452 CLLs and 54 monoclonal B-lymphocytosis (MBL), a pre...
EGAS00001001306 | EGA
Genomicsena-DATASET-Hospital Clinic Barcelona-12-08-2015-11:33:40:243-146 - samples
Exome Sequencing. 3 μg of genomic DNA from each sample were sheared and used for the construction of a paired-end sequencing library as described in the paired-end sequencing sample preparation protocol provided by Illumina41. Enrichment of exonic sequences was then performed for each library usi...
EGAD00001001464 | EGA
Genomicsena-DATASET-Hospital Clinic Barcelona-13-08-2015-12:02:30:199-229 - samples
Whole Genome sequencing. 2 μg of genomic DNA from each sample was used for the construction of two short-insert paired-end sequencing libraries. Both types of libraries were sequenced in paired-end mode on Illumina GAIIx (2 × 151 bp) using Sequencing kit v4 or Illumina HiSeq2000 (2x101 bp) usi...
EGAD00001001466 | EGA
UnknownA multi-tissue study of immune gene expression profiling highlights the key role of the nasal epithelium in COVID-19 severity.
Not available
S-EPMC8861187 | biostudies-literature
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