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ProteomicsTargeting APEX2 to the mRNA encoding fatty acid synthase β in yeast identifies proteins that bind and control its translational efficiency in the cell cycle
To understand how the translation of FAS1, encoding fatty acid synthase, peaks late in the cell cycle, we identified proteins that bind the FAS1 transcript in a cell cycle-dependent manner. We used dCas13d-APEX2 fusions to target FAS1 and label nearby proteins, which were then identified by mass spe...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-05-24 | PXD041908 | Pride
Yeast  lc-ms/ms  proximity labeling 
Metabolomics3D'omics: Salmonella challenge chicken trial

BioProject PRJEB86258 at https://www.ebi.ac.uk/ena/browser/view/PRJEB86258


The full study description is published in detail before:

Poult Sci. 2025 Feb 6;104(4):104890. doi: 10.1016/j.psj.2025.104890

“Differential effects of synbiotic delivery route (Feed, water, com...

2025-11-19 | MTBLS13315 | MetaboLights
UnknownuORF-mediated translational control of CAK and Cdk activation in response to low nutrients in yeast
Not available
S-SCDT-10_1038-S44319-026-00916-Z | biostudies-other
ProteomicsADAR1 interactome analysis, LC-MS/MS
Adenosine-to-inosine (A-to-I) RNA editing catalyzed by ADAR1 plays essential roles in the regulation of diverse molecular and cellular processes both under physiological conditions and in the disease states, including cancer. However, mechanisms governing the protein abundance and activity of ADAR1,...
ORGANISM(S): Homo sapiens (Human) 
2022-05-29 | PXD025338 | Pride
Human embryonic kidney hek-293t cells lc-ms/ms 
ProteomicsLC-MS/MS for identification on ADAR1p110 the sites of ubiquitin conjugation
Adenosine-to-inosine (A-to-I) RNA editing catalyzed by ADAR1 plays essential roles in the regulation of diverse molecular and cellular processes both under physiological conditions and in the disease states, including cancer. However, mechanisms governing the protein abundance and activity of ADAR1,...
ORGANISM(S): Homo sapiens (Human) 
2022-05-29 | PXD025325 | Pride
Human embryonic kidney hek-293t cells Lc-ms/ms 
MetabolomicsLongitudinal multi-omics reveals subset-specific mechanisms underlying irritable bowel syndrome

The gut microbiome has been implicated in multiple human chronic gastrointestinal (GI) disorders. Determining its mechanistic role in disease has been difficult due to apparent disconnects between animal and human studies and lack of an integrated multi-omics view of disease-specific physiologica...

2020-09-08 | MTBLS1396 | MetaboLights
UnknownBranched-chain amino acid synthesis is coupled to TOR activation early in the cell cycle in yeast
Not available
S-SCDT-10_15252-EMBR_202357372 | biostudies-other
TranscriptomicsThe Pitx2:miR-200c/141:noggin pathway regulates BMP signaling and ameloblast differentiation
The mouse incisor is a remarkable tooth that grows throughout the animalM-bM-^@M-^Ys lifetime. This continuous renewal is fueled by epithelial stem cells that give rise to ameloblasts, which generate enamel, and little is known about the function of specific miRNAs in this process. Here we describe ...
ORGANISM(S): Mus musculus 
2013-07-09 | E-GEOD-48583 | biostudies-arrayexpress
MetabolomicsMetabolic Dynamics of In Vitro CD8+ T Cell Activation

CD8+ T cells detect and kill virally infected or cancerous cells. When activated from their naïve state, T cells undergo a complex transition, including major metabolic reprogramming. Detailed resolution of metabolic dynamics of a wide range of metabolites is needed to advance the field of immuno...

2021-06-02 | MTBLS2145 | MetaboLights
MetabolomicsDeletion of glycerol channel aquaporin-9 (Aqp9) impairs long-term blood glucose control in C57BL/6 leptin receptor-deficient (db/db) obese mice
Deletion of the glycerol channel aquaporin-9 (Aqp9) reduces postprandial blood glucose levels in leptin receptor deficient (db/db) obese mice on a C57BL/6×C57BLKS mixed genetic background. Furthermore, shRNA mediated reduction of Aqp9 expression reduces liver triacylglycerol (TAG) accumulation in a ...
2015-09-28 | MTBLS219 | MetaboLights
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