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TranscriptomicsGenetic Determinants for Susceptibility to Staphylococcus aureus Infection in A/J and C57BL/6J
Although it has recently been shown that A/J mice are highly susceptible to Staphylococcus aureus sepsis as compared to C57BL/6J, the specific genes responsible for this differential phenotype are unknown. Using chromosome substitution strains (CSS), we found that factors on chromosomes (chr) 8, 11,...
ORGANISM(S): Mus musculus 
2010-08-01 | E-GEOD-19668 | biostudies-arrayexpress
TranscriptomicsMechanisms of CS-related A/J lung tumorigenesis
The A/J mouse is highly susceptible to lung tumor induction and has been widely used as a screening system in carcinogenicity testing and chemoprevention studies. However, the A/J mouse model has several disadvantages. Most notably, it develops tumors spontaneously. Moreover, there is a considerable...
ORGANISM(S): Mus musculus 
2014-08-29 | E-MTAB-1871 | biostudies-arrayexpress
UnknownThe histone methyltransferase Setd2 is indispensable for V(D)J recombination.
Not available
S-EPMC6659703 | biostudies-literature
UnknownNovel changes in glycosylation of serum Apo-J in patients with hepatocellular carcinoma.
Not available
S-EPMC3111882 | biostudies-literature
UnknownConcomitant SK current activation and sodium current inhibition cause J wave syndrome.
Not available
S-EPMC6302939 | biostudies-literature
GenomicsCSL ChIP-seq
The expression of a large proportion of the fission yeast genome changes periodically with the cell cycle. Several key transcription factors have been identified that regulate these oscillating and interdependent waves of gene expression. However, for a significant number of cell cycle-regulated gen...
ORGANISM(S): Schizosaccharomyces pombe 
2015-09-18 | E-MTAB-2725 | biostudies-arrayexpress
TranscriptomicsGene Expression Data Following Chronic Vehicle or Fluoxetine Treatment in Thirty Mouse Inbred Lines
In order to understand how biochemical and genetic differences correlate with treatment response, we measured depressive-like behavior, gene expression and the levels of thirty-six neurobiochemical analytes across a panel of genetically-diverse mouse inbred lines after chronic treatment with vehicle...
ORGANISM(S): Mus musculus 
2011-08-30 | E-GEOD-28644 | biostudies-arrayexpress
TranscriptomicsDietary folate depletion and repletion in A/J and C57BL/6J mice
Defects in homocysteine and folate metabolism are associated with increased risks for neural tube and congenital heart defects, cardiovascular disease and stroke, cancers, and neurodegeneration. In many but not all cases, dietary supplementation with folate significantly reduces the severity and in...
ORGANISM(S): Mus musculus 
2008-08-27 | E-GEOD-9242 | biostudies-arrayexpress
UnknownLoss of H3K36 Methyltransferase SETD2 Impairs V(D)J Recombination during Lymphoid Development.
Not available
S-EPMC7066224 | biostudies-literature
UnknownJ domain-independent regulation of the Rb family by polyomavirus large T antigen.
Not available
S-EPMC110883 | biostudies-literature
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