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TranscriptomicsTetracyclines Specifically Target the Apicoplast of the Malaria Parasite Plasmodium falciparum
Tetracyclines are effective but slow-acting antimalarial drugs whose mechanism of action remains uncertain. To characterize the antimalarial mechanism of tetracyclines, we evaluated their stage-specific activities, impacts on parasite transcription, and effects on two predicted organelle targets, th...
ORGANISM(S): Plasmodium falciparum 
2010-07-01 | E-GEOD-5267 | biostudies-arrayexpress
UnknownDisparities in Distribution of Particulate Matter Emission Sources by Race and Poverty Status.
Not available
S-EPMC5844406 | biostudies-literature
TranscriptomicsTranscription profiling of earthworm Lumbrius rubellus after treatment with a sub-lethal dose of cadmium
To determine the transcriptome sub-lethal dose response profile for adult Lumbricus rubellus exposued to Cadmium.
ORGANISM(S): synthetic 
2007-12-17 | E-MAXD-34 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of rat SJL sub-strains of an experimental autoimmune encephalomyelitis (EAE) rodent model of Multiple Sclerosis (MS)
Copy number variation in two SJL sub-strains of an experimental autoimmune encephalomyelitis (EAE) rodent model of Multiple Sclerosis (MS)
ORGANISM(S): Mus musculus 
2010-02-26 | E-MEXP-2534 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Lumbricus rubellus to determine seasonal changes in gene expression
To determine the developmental and seasonal variation in transcript expression within a terrestial sentinal, the earthworm Lumbricus rubellus.
ORGANISM(S): synthetic_DNA 
2008-01-08 | E-MAXD-36 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Lumbricus rubellus exposed to the herbicide atrazine to determine the sub lethal dose
To determine the transcriptome sub-lethal dose response profile for adult Lumbricus rubellus exposued to Atrazine.
ORGANISM(S): Lumbrius rubellus 
2007-12-21 | E-MAXD-35 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of adult red earthworms, Lumbricus rubellus, following a sub-lethal dose of fluroanthene
To determine the transcriptome sub-lethal dose response profile for adult Lumbricus rubellus exposued to Fluoranthene.
ORGANISM(S): Lumbrius rubellus 
2007-11-01 | E-MAXD-31 | biostudies-arrayexpress
TranscriptomicsImmunotherapy Targets in Tumors
Recent work has shown that cytotoxic T cells play a central role in immune-mediated control of cancers1-3, and monoclonal antibodies that target inhibitory receptors on T cells can induce significant clinical benefit in patients despite advanced disease4-6. However, many of the regulatory pathways t...
ORGANISM(S): Mus musculus 
2014-03-14 | E-GEOD-53388 | biostudies-arrayexpress
ProteomicsNanochip proteome of Klebsiella
In this study, we used an interdisciplinary approach, combining biophysics and systems biology, to design a microfluidic chip for the multiplexed detection and separation of pathogen cells from immune cells combined with proteomic profiling using mass spectrometry. Our nanochip design includes preci...
ORGANISM(S): Klebsiella pneumoniae subsp. pneumoniae 
2026-03-21 | PXD058426 | Pride
Quantitative proteomics Microfluidics Klebsiella pneumoniae Nanochip technology Macrophages Anti-virulence Systems biology 
TranscriptomicsInhibitors that block initiation of wall teichoic acid biosynthesis sensitize methicillin-resistant Staphylococcus aureus to beta-lactams
Methicillin resistance in Staphylococcus aureus depends on the production of mecA, which encodes penicillin-binding protein 2A (PBP2A), an acquired peptidoglycan transpeptidase with reduced susceptibility to beta-lactam antibiotics. Here, we show that preventing the expression of wall teichoic acids...
ORGANISM(S): Staphylococcus aureus 
2010-10-19 | E-GEOD-24439 | biostudies-arrayexpress
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