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GenomicsUltrasound-mediated blood–spinal cord barrier opening prolongs survival in an ALS mouse model
Ultrasound-mediated blood–spinal cord barrier opening prolongs survival in an ALS mouse model
PRJNA1124127 | ENA
UnknownImproved locomotor recovery after contusive spinal cord injury in Bmal1-/- mice is associated with protection of the blood spinal cord barrier.
Not available
S-EPMC7450087 | biostudies-literature
TranscriptomicsComparative genomic hybridization by array of rat brain- and spinal cord-derived microvascular endothelial cells, in basal and inflammatory conditions upon different time points of TNF-α-treatment or TWEAK-treatment or LPS-treatment.
The brain and spinal cord are endowed with particular vascular systems, known as the blood-brain barrier (BBB) and blood-spinal cord barrier (BSCB) respectively, which maintain homeostasis between nervous parenchyma and peripheral circulation. Despite these common features, the BSCB presents structu...
ORGANISM(S): Rattus norvegicus 
2016-06-20 | E-MTAB-4696 | biostudies-arrayexpress
UnknownSIRT1 attenuates blood-spinal cord barrier disruption after spinal cord injury by deacetylating p66Shc.
Not available
S-EPMC9900454 | biostudies-literature
UnknownBlood-spinal cord barrier leakage is independent of motor neuron pathology in ALS.
Not available
S-EPMC8393479 | biostudies-literature
TranscriptomicsUltrasound-mediated blood–spinal cord barrier opening prolongs survival in an ALS mouse model
Background: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by a progressive loss of motor neurons. The limited efficacy of recent therapies in clinical development may be linked to lack of drug penetration to the affected motor neurons due to the blood-brain b...
ORGANISM(S): Mus musculus 
2024-07-15 | GSE269925 | GEO
UnknownPathological hemodynamic changes and leukocyte transmigration disrupt the blood-spinal cord barrier after spinal cord injury.
Not available
S-EPMC10200062 | biostudies-literature
UnknownTreg cells-derived exosomes promote blood-spinal cord barrier repair and motor function recovery after spinal cord injury by delivering miR-2861.
Not available
S-EPMC10552208 | biostudies-literature
UnknownCO-Releasing Molecule (CORM)-3 Ameliorates Spinal Cord-Blood Barrier Disruption Following Injury to the Spinal Cord.
Not available
S-EPMC7287126 | biostudies-literature
UnknownDelayed administration of nafamostat mesylate inhibits thrombin-mediated blood-spinal cord barrier breakdown during acute spinal cord injury in rats.
Not available
S-EPMC9287720 | biostudies-literature
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