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TranscriptomicsThe chromatin-modifying enzyme Ezh2 is a CD28-dependent molecule critical for the maintenance of Treg identity
Regulatory T cells (Tregs) are essential for maintaining proper immune homeostasis. Extracellular signals (e.g. TCR, CD28, IL-2R) are necessary for the generation and maintenance of Tregs, but how these signals are integrated to control the gene expression patterns of Tregs is less clear. Here we sh...
ORGANISM(S): Mus musculus 
2015-02-09 | E-GEOD-58998 | biostudies-arrayexpress
TranscriptomicsmiRNA expression in CD4+CD25- conventional (Tconv) and CD4+CD25+ regulatory T (Treg) cells
miRNA expression profiling in highly purified murine CD4+ Tconv and Treg cells. FoxP3-GFP-hCre1a(high) reporter mice were used to separate both populations based on surface markers and presence or absence of GFP. Two-condition experiment, Tconv vs. Treg. Biological replicates: 1 Tconv, 1 Treg, purif...
ORGANISM(S): Mus musculus 
2013-06-06 | E-GEOD-30847 | biostudies-arrayexpress
UnknownPolymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency.
Not available
S-EPMC6954310 | biostudies-literature
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