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MetabolomicsApolipophorin-III modulates antiviral defense in Bombyx mori: an integrated transcriptomic and lipidomic analysis of its inhibitory role against BmNPV infection.

The silkworm (Bombyx mori) is an economically important insect and a lepidopteran model organism. Controlling viral infections is crucial for the sustainable development of sericulture. Bombyx mori nucleopolyhedrovirus (BmNPV) infection can cause large-scale mortality in silkworm populations. Ins...

2025-12-03 | MTBLS13447 | MetaboLights
ProteomicsQuantitative proteomics of Bombyx mori after BmNPV challenge
Employed BmN cell after 10 MOI (multiplicity of infection) BmNPV 36 hpi (hour post-infection) to compare the proteomics by LC-MS/MS
ORGANISM(S): Bombyx mori (Silk moth) 
2018-05-22 | PXD008856 | Pride
Bombyx mori  bmnpv  moleccular function  biological process 
TranscriptomicsGenome wide microarray based expression profiles associated with BmNPV resistantance and susceptibility in Indian silkworm races of Bombyx mori
The molecular mechanism involved in BmNPV resistance was investigated using a genome wide microarray in the midgut tissues of BmNPV infected resistant (Sarupat) and susceptible (CSR-2) Indian silkworm races. In the resistant race, 735 genes were upregulated and 589 genes were down regulated at 12 ho...
ORGANISM(S): Bombyx mori 
2016-07-01 | E-GEOD-71240 | biostudies-arrayexpress
TranscriptomicsFunctional analysis of BmNPV cis-interacting sites
RNA-seq of BmNPV cells infected by indicated mutant BmNPV to determine the impact on viral gene expression of the cis-interacting sites on BmNPV by knocking out them via RED system
ORGANISM(S): Bombyx mori 
2024-10-01 | GSE278147 | GEO
TranscriptomicsBombyx mori UFBP1 regulates apoptosis and promotes BmNPV proliferation by affecting the expression of ER chaperone BIP
Ubiquitin-fold modifier 1 (UFM1) is attached to protein substrates through the sequential activity of an E1 (UBA5)-E2 (UBC1)-E3 (UBL1) cascade. UFBP1 is a conserved UFL1-interacting protein in mammals. However, there is no study on UFBP1 in silkworm yet. In this study, we identified a UFBP1 ortholog...
ORGANISM(S): Bombyx mori 
2024-07-31 | GSE272804 | GEO
TranscriptomicsPrecocious metamorphosis of silkworm by BmNPV infection in the latter half of the fifth instar larvae
The silkworm, Bombyx mori, is a complete metamorphosis insect and an economically important for silk production, the model to study insect physiology and biochemistry. Bombyx mori nucleopolyhedrovirus (BmNPV) is a principal pathogen of the silkworm and its host range is restricted to silkworm larvae...
ORGANISM(S): Bombyx mori 
2021-03-02 | GSE167875 | GEO
TranscriptomicsGenome wide microarray based expression profiles associated with BmNPV resistantance and susceptibility in Indian silkworm races of Bombyx mori
The molecular mechanism involved in BmNPV resistance was investigated using a genome wide microarray in the midgut tissues of BmNPV infected resistant (Sarupat) and susceptible (CSR-2) Indian silkworm races. In the resistant race, 735 genes were upregulated and 589 genes were down regulated at 12 ho...
ORGANISM(S): Bombyx mori 
2016-07-01 | GSE71240 | GEO
UnknownPathogenicity Detection and Genome Analysis of Two Different Geographic Strains of BmNPV.
Not available
S-EPMC8537803 | biostudies-literature
GenomicsPrecocious metamorphosis of silkworm by BmNPV infection in the latter half of the fifth instar larvae
Precocious metamorphosis of silkworm by BmNPV infection in the latter half of the fifth instar larvae
PRJNA705370 | ENA
GenomicsBombyx mori UFBP1 regulates apoptosis and promotes BmNPV proliferation by affecting the expression of ER chaperone BIP
Bombyx mori UFBP1 regulates apoptosis and promotes BmNPV proliferation by affecting the expression of ER chaperone BIP
PRJNA1138767 | ENA
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