Sort   by:  
 Page size 
TranscriptomicsEffects of RGMc on BMP2 and BMP6-mediated Gene Expression in Hep3B Liver Cells
Mutations in repulsive guidance molecule c (RGMc) / hemojuvelin (HJV) cause juvenile hemochromatosis, an aggravated iron overload disorder that presents early in life. Patients with juvenile hemochromatosis, and RGMc knockout mice, have diminished expression of the key iron-regulatory peptide, hepc...
ORGANISM(S): Homo sapiens 
2010-06-23 | E-GEOD-20671 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human mesenchymal stem cells treated for 8 hours with BMP6
We have established that BMP6 is an important endogenous regulator of human osteoblast differentiation. Our preliminary experiment showed that 8 hour BMP6 treatment induced early osteoblast markers in hMSC. In this study, we used microarrays to profile the global gene expression program in hMSC indu...
ORGANISM(S): Homo sapiens 
2009-06-08 | E-GEOD-13604 | biostudies-arrayexpress
TranscriptomicsA time series study on BMP6 induced osteoblast differentiation of human mesenchymal stem cells (hMSC)
BMP6 mediated osteoblast differentiation plays a key role in skeletal development and bone disease. Unfortunately, the signaling pathways regulated by BMP6 are largely uncharacterized due to both a lack of data and the complexity of the response. To better characterize the signaling pathways respons...
ORGANISM(S): Homo sapiens 
2011-09-19 | E-GEOD-28074 | biostudies-arrayexpress
GenomicsTranscriptome analysis of melanoma cells stably expressing BMP6
Transcriptome analysis of melanoma cells stably expressing BMP6
PRJNA690945 | ENA
GenomicsEndothelial BMP6 Drives Hemodynamic-Dependent VSMCs Calcification in Carotid Atherosclerosis
Endothelial BMP6 Drives Hemodynamic-Dependent VSMCs Calcification in Carotid Atherosclerosis
PRJNA1336120 | ENA
TranscriptomicsEndothelial BMP6 Drives Hemodynamic-Dependent VSMCs Calcification in Carotid Atherosclerosis
Carotid atherosclerosis (CAS) is a major contributor to ischemic stroke, with vascular calcification driving disease progression. However, the molecular mechanisms driving vascular calcification in CAS remain unelucidated. Previous studies have confirmed that bone morphogenetic proteins (BMPs) play ...
ORGANISM(S): Homo sapiens Mus musculus 
2025-10-03 | GSE309462 | GEO
TranscriptomicsTranscriptome analysis of melanoma cells stably expressing BMP6
Molecular function of BMPs in metastatic melanoma progression is undefined. The goal of this study is to identify BMP6-activated gene signaturs associated with metastatic progresses in human cutaneous melanoma. Transcriptome profiles (RNA-seq) of three melanoma cell lines (WM1341D, WM983B, and 1205L...
ORGANISM(S): Homo sapiens 
2021-01-10 | GSE164495 | GEO
GenomicsLiver sinusoidal endothelial cells induce BMP6 expression in response to non-transferrin bound iron
Liver sinusoidal endothelial cells induce BMP6 expression in response to non-transferrin bound iron
PRJNA889768 | ENA
GenomicsNRF2-independent iron-triggered signaling via MAPK p38-ETS1 regulates LSEC Bmp6 mRNA expression [I]
NRF2-independent iron-triggered signaling via MAPK p38-ETS1 regulates LSEC Bmp6 mRNA expression [I]
PRJNA986911 | ENA
GenomicsNRF2-independent iron-triggered signaling via MAPK p38-ETS1 regulates LSEC Bmp6 mRNA expression [II]
NRF2-independent iron-triggered signaling via MAPK p38-ETS1 regulates LSEC Bmp6 mRNA expression [II]
PRJNA988116 | ENA
Sort   by:  
 Page size