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ModelsBoer1986 - Interactions between Macrophages and T-lymphocytes: Tumor Sneaking Through Intrinsic to Helper T cell Dynamics
Interactions between Macrophages and T-lymphocytes: Tumor Sneaking Through Intrinsic to Helper T cell Dynamics ROB J. DE BOER AND PAULINE HOGEWEG Bioinformatics Group, University of Utrecht, Padualaan 8, 3584 CH Utrecht, The Netherlands Abstract In a mathematical model of the cellular immune respo...
2019-12-11 | MODEL1912110001 | BioModels
Immuno-oncology 
UnknownRisk of bias in studies investigating novel diagnostic biomarkers for heart failure with preserved ejection fraction. A systematic review.
Not available
S-EPMC7689920 | biostudies-literature
TranscriptomicsTranscription profling of infants (<1 year of age) diagnosed with Acute Lymphoblastic Leukemia (ALL) characterised by genomic translocation.
Acute Lymphoblastic Leukemia (ALL) in infants (<1 year) is characterized by a poor prognosis and a high incidence of MLL translocations. Several studies demonstrated the unique gene expression profile associated with MLL-rearranged ALL, but generally small cohorts were analyzed as uniform patient gr...
ORGANISM(S): Homo sapiens 
2009-12-15 | E-GEOD-19475 | biostudies-arrayexpress
UnknownGalectin-3 and Risk of Late Graft Failure in Kidney Transplant Recipients: A 10-year Prospective Cohort Study.
Not available
S-EPMC8078111 | biostudies-literature
TranscriptomicsEarly divergence of Th1 and Th2 transcriptomes involves a small core response and sets of transiently expressed genes
Helper T cells can adopt a number of different phenotypes. We performed microarray-assisted mRNA profiling on antigen-stimulated, TCR transgenic murine splenocytes that were cultured in the presence of cytokines. Transcriptome snapshots of Th cells differentiating into Th1 and Th2 phenotypes were o...
ORGANISM(S): Mus musculus 
2013-03-01 | E-MTAB-1475 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human CEM_C1 cells after rapamycin treatment of 24 hours
Drug resistance remains a major obstacle to successful cancer treatment. Here we use a novel approach to identify rapamycin as a glucocorticoid resistance reversal agent. A database of drug-associated gene expression profiles was screened for molecules whose profile overlapped with a gene expression...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-5821 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human pretreatment glucocortocoid sensitive and resistant primary leukaemias
Drug resistance remains a major obstacle to successful cancer treatment. Here we use a novel approach to identify rapamycin as a glucocorticoid resistance reversal agent. A database of drug-associated gene expression profiles was screened for molecules whose profile overlapped with a gene expression...
ORGANISM(S): Homo sapiens 
2009-04-04 | E-GEOD-5820 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human CEM-C1 cells treate with rapamycin for 3 hours
Drug resistance remains a major obstacle to successful cancer treatment. Here we use a novel approach to identify rapamycin as a glucocorticoid resistance reversal agent. A database of drug-associated gene expression profiles was screened for molecules whose profile overlapped with a gene expression...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-5822 | biostudies-arrayexpress
TranscriptomicsTransduced cord blood CD34+ cells with empty vector, AML1-ETO and ETV6-RUNX1
Mononuclear cells were isolated from umbilical cord blood (UCB) using Lymphoprep sucrose-gradient centrifugation (1.077 g/ml, Nycomed Pharma, Oslo, Norway). Immunomagnetic cell separation, using magnetic beads coated with CD34 antibodies (Miltenyi Biotec, Gladbach, Germany), was performed to isolate...
ORGANISM(S): Homo sapiens 
2019-01-01 | E-MTAB-3466 | biostudies-arrayexpress
TranscriptomicsTranscription profiling and proteomic profiling of rat colon mucosa from rats fed quercetin
Quercetin has been shown to act as an anti-carcinogen in experimental colorectal cancer (CRC). The aim of the present study was to characterise transcriptome and proteome changes occurring in the distal colon mucosa of rats supplemented with 10 g quercetin/kg diet for 11 weeks. Transcriptome data an...
ORGANISM(S): Rattus norvegicus 
2008-06-15 | E-GEOD-7479 | biostudies-arrayexpress
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