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GenomicsSpi-1/PU.1 activates transcription through clustered DNA occupancy in erythroleukemia
Acute leukemia are characterized by deregulation of transcriptional networks that control the lineage specificity of gene expression. The aberrant overexpression of the Spi-1/PU.1 transcription factor leads to erythroleukemia. To determine how Spi-1 mechanistically influences the transcriptional pro...
ORGANISM(S): Mus musculus 
2012-06-30 | E-GEOD-33611 | biostudies-arrayexpress
GenomicsAnalysis of the recruitment of JARID2 via Xist RNA during XCI by ChIP-seq
JARID2 ChIP-seq profile mediated by Xist was investigated using two separate approaches: In the first approach, we use the TX1072 female embryonic stem cell (ESC) line; this is a genetically polymorphic ESC line derived from a mouse with one X-chromosome (X-chr) from the Mus musculus castaneus (Cast...
ORGANISM(S): Mus musculus 
2014-01-23 | E-GEOD-52073 | biostudies-arrayexpress
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