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TranscriptomicsTime-series of IL-6 stimulated primary mouse hepatocytes
External stimulations of cells by hormones, growth factors or cytokines activate signal transduction pathways that subsequently induce a rearrangement of cellular gene expression. The representation and analysis of changes in the gene response is complicated, and essentially consists of multiple lay...
ORGANISM(S): Mus musculus 
2010-04-07 | E-GEOD-21031 | biostudies-arrayexpress
TranscriptomicsIL13_0-12h_RAIA_et_al
Primary mediastinal B-cell lymphoma (PMBL) and classical Hodgkin lymphoma (cHL) share a frequent constitutive activation of Janus-activated kinase (JAK) / signal transducer and activator of transcription (STAT) signaling pathway. Due to complex non-linear relations within the pathway, key dynamic pr...
ORGANISM(S): Homo sapiens 
2010-12-09 | E-GEOD-23591 | biostudies-arrayexpress
ModelsRaia2011 - IL13 L1236
This is the model of IL13 induced signalling in L1236 cells described in the article: Dynamic Mathematical Modeling of IL13-Induced Signaling in Hodgkin and Primary Mediastinal B-Cell Lymphoma Allows Prediction of Therapeutic Targets. Raia V, Schillin...
2024-09-02 | BIOMD0000000314 | BioModels
ModelsRaia2010 - IL13 Signalling MedB1
This is the model of IL13 induced signalling in MedB-1 cell described in the article: Dynamic Mathematical Modeling of IL13-Induced Signaling in Hodgkin and Primary Mediastinal B-Cell Lymphoma Allows Prediction of Therapeutic Targets. Raia V, Schilling M, Böhm M, Hahn B, Kowarsch A,...
2024-09-02 | BIOMD0000000313 | BioModels
ModelsSobotta2017 - IL-6-induced JAK1-STAT3-signaling
Here we present a mathematical model of IL-6-induced JAK1-STAT3 signaling that quantitatively links physiological IL-6 concentrations to the dynamics of IL-6-induced signal transduction and expression of target genes in hepatocytes. The mathematical model consists of coupled ordinary differential eq...
2023-07-05 | MODEL2307050001 | BioModels
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