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TranscriptomicsGenotyping of human primary acute myeloid leukemia cells on the Affymetrix 6.0 SNP array to validate direct sequecing of the TET2 locus in genomic DNA
The TET2 locus was analyzed for DNA copy number, and LOH using a large set of paired samples (n=106), i.e. AML cells at diagnosis and normal peripheral blood mononuclear cells at remission; and AML at diagnosis (n=6). Affymetrix 6.0 SNP array were used.
ORGANISM(S): Homo sapiens 
2010-06-01 | E-MTAB-278 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human blood from acute promyelocytic leukemia patients using different differentiating agents
Differentiating agents have been proposed to overcome the impaired cellular differentiation in acute myeloid leukemia (AML). However, only the combinations of all-trans retinoic acid or arsenic trioxide with chemotherapy have been successful, and only in treating acute promyelocytic leukemia (also c...
ORGANISM(S): Homo sapiens 
2010-03-23 | E-TABM-925 | biostudies-arrayexpress
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