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TranscriptomicsModulation of EDA2R/EDA-A2 signalling in Human Myoblasts
Transfection of human myoblasts was performed using Lipofectamine or electroporation. Skeletal muscle myoblasts isolated from a human male donor were transfected using the Lipofectamine™ 2000 Transfection Reagent (Invitrogen, 11668019). Twenty-four hours before transfections, cells were plated to a ...
ORGANISM(S): Homo sapiens 
2024-09-13 | E-MTAB-14239 | biostudies-arrayexpress
UnknownP1144: RADIOIMMUNOTHERAPY (RIT) VERSUS AUTOLOGOUS HEMATOPOIETIC STEM-CELL TRANSPLANTATION (ASCT) IN RELAPSED/REFRACTORY (R/R) FOLLICULAR LYMPHOMA: A FONDAZIONE ITALIANA LINFOMI (FIL) PHASE III TRIAL.
Not available
S-EPMC9430496 | biostudies-literature
TranscriptomicsC2C12 Murine Myoblasts over-expressing Eda2r
C2C12 (ATCC, #CRL-1772), a myoblast cell line from the C3H mouse strain, was grown in DMEM (Dulbecco’s Modified Eagle’s Medium, Gibco), supplemented with 10% fetal bovine serum (FBS) (Euroclone, Pero, Italy) and 2 mM L-glutamine (Gibco), and maintained in culture at 37 °C with 5% CO₂, without reachi...
ORGANISM(S): Mus musculus 
2023-09-01 | E-MTAB-13101 | biostudies-arrayexpress
UnknownBrentuximab Vedotin and Bendamustine Produce Long-Term Clinical Benefit in Patients With Relapsed or Refractory Classical Hodgkin Lymphoma: A Multicenter Real-Life Experience.
Not available
S-EPMC9531864 | biostudies-literature
TranscriptomicsRNA-sequencing of prostate cancer xenografts, their 3D cultures and prostate cancer cell-lines.
RNA-sequencing of prostate cancer xenografts, their 3D cultures and prostate cancer cell-lines.
ORGANISM(S): Homo sapiens 
2021-09-29 | E-MTAB-9930 | biostudies-arrayexpress
TranscriptomicsInhibition of ketohexokinase C isoform impairs the development of PDAC tumors
the genetic inactivation of Khk-C enhanced the survival of KPC-driven PDAC model even in absence of high fructose diet. Moreover Khk-C knock out decreased the viability of KPC organoids and cancer cells, the migratory capability of PDAC cells in vitro and the growth of KPC cells in vivo in a cell au...
ORGANISM(S): Mus musculus 
2023-07-07 | E-MTAB-12746 | biostudies-arrayexpress
TranscriptomicsStable overexpression and knockdown of mutant- or wild type SPOP in VCaP prostate cancer cells
Purpose: Little is known about the interplay of driver mutations that never co-occur within the same cancer cells. The latter scenario has been identified in prostate cancer where recurrent gene fusions involving the oncogenic ERG transcription factor and point mutations in the ubiquitin ligase adap...
ORGANISM(S): Homo sapiens 
2020-12-05 | E-MTAB-7165 | biostudies-arrayexpress
TranscriptomicsStable over expression of the SPOP-substrate ZMYND11 in VCaP cells
SPOP is known to bind to serine/theronine-rich degrons on substrate proteins. We identified two degron sequences within the PWWP and MYND domain of ZMYND11, a novel SPOP substrate, and investigated whether ZMYND11 may contribute to the transcriptional output of mutant SPOP in VCaP cancer cells. Henc...
ORGANISM(S): Homo sapiens 
2020-12-16 | E-MTAB-7173 | biostudies-arrayexpress
TranscriptomicsStable overexpression of either mutant- or wild type SPOP in presence/absence of ΔERG in LNCaP prostate cancer cells
Purpose: Little is known about the interplay of driver mutations that never co-occur within the same cancer cells. The latter scenario has been identified in prostate cancer where recurrent gene fusions involving the oncogenic ERG transcription factor and point mutations in the ubiquitin ligase adap...
ORGANISM(S): Homo sapiens 
2020-12-10 | E-MTAB-7170 | biostudies-arrayexpress
UnknownTIP5 primes prostate luminal cells for the oncogenic transformation mediated by PTEN-loss.
Not available
S-EPMC7035629 | biostudies-literature
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