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TranscriptomicsA calcium-induced signaling cascade leading to osteogenic differentiation of human bone marrow-derived mesenchymal stromal cells
The response of osteoprogenitors to calcium (Ca2+) is of primary interest for both normal bone homeostasis and the clinical field of bone regeneration. The latter makes use of calcium phosphate-based bone void fillers to heal bone defects, but it is currently not known how Ca2+ released from these c...
ORGANISM(S): Homo sapiens 
2018-10-06 | E-MTAB-7222 | biostudies-arrayexpress
TranscriptomicsExtracellular purines promote the differentiation capacity of human bone marrow-derived mesenchymal stem cells
Extracellular nucleotides are potent signaling molecules mediating cell-specific biological functions. We previously demonstrated that adenosine 5'-triphosphate (ATP) inhibits the proliferation while stimulating the migration, in vitro and in vivo, of human bone marrow-derived mesenchymal stem cells...
ORGANISM(S): Homo sapiens 
2013-04-11 | E-GEOD-37237 | biostudies-arrayexpress
UnknownBone marrow-derived human mesenchymal stem cells express cardiomyogenic proteins but do not exhibit functional cardiomyogenic differentiation potential.
Not available
S-EPMC3425038 | biostudies-literature
UnknownCharacterization of patient-derived bone marrow human mesenchymal stem cells as oncolytic virus carriers for the treatment of glioblastoma.
Not available
S-EPMC10193507 | biostudies-literature
UnknownExtracellular purines promote the differentiation of human bone marrow-derived mesenchymal stem cells to the osteogenic and adipogenic lineages.
Not available
S-EPMC3608030 | biostudies-literature
ProteomicsQuantitative Proteomics Reveals Metabolic Differences in Homing and Non-Homing Glioma Stem Cell Xenografts and Stromal Cells
Glioblastoma is the most common and most devastating adult primary brain tumor. Despite aggressive multimodal therapy, the median survival is approximately one year after diagnosis. In recent years bone marrow-derived human mesenchymal stem cells (BM-hMSCs) have shown promise as cell-based delivery ...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) Homo sapiens/Mus musculus xenograft 
2016-02-17 | PXD001778 | Pride
Fatty acid metabolism glycolysis Glycosylation Pentose phosphate pathway Mass spectrometry Cancer proteomics Glioblastoma Bone marrow-derived human mesenchymal stem cells (bm-hmscs) Transcriptomics 
UnknownA Glycovariant of Human CD44 is Characteristically Expressed on Human Mesenchymal Stem Cells.
Not available
S-EPMC5367967 | biostudies-literature
TranscriptomicsExtremely low frequency electromagnetic fields enhance neuronal differentiation of human mesenchymal stem cells on graphene-based substrate
Graphene-based substrate has efficient neuronal differentiation of hMSCs. Stimulatory effects of graphene on hMSCs neurogenesis can be enhanced by ELF-EMF exposure and it is mediated by enhancement of cell adhesion accompanied by intracellular signal pathway. We used microarrays to assess up-regulat...
ORGANISM(S): Homo sapiens 
2014-12-23 | E-GEOD-64416 | biostudies-arrayexpress
UnknownSerum-mediated Activation of Bone Marrow-derived Mesenchymal Stem Cells in Ischemic Stroke Patients: A Novel Preconditioning Method.
Not available
S-EPMC6038038 | biostudies-literature
UnknownDNMT3B Is an Oxygen-Sensitive De Novo Methylase in Human Mesenchymal Stem Cells.
Not available
S-EPMC8145390 | biostudies-literature
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