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TranscriptomicsTranscriptome of GATA3 knocked-down and normal keratinocytes after 1 cGy X irradiation
To characterize the consequences of the GATA3 silencing on the transcriptome of X-rays irradiated keratinocytes. Oligonuclotide microarrays were used to assess transcriptional changes over a time-course between 3 and 72h post-irradiation in a GATA3 knocked-down background (shGATA3) or in a normal ba...
ORGANISM(S): Homo sapiens 
2010-05-05 | E-GEOD-15716 | biostudies-arrayexpress
TranscriptomicsImmune Response of Immature Dendritic Cells after Infection with Human Cytomegalovirus Strain TB40E
Microarray analysis and quantitative real-time PCR revealed that TB40E infection of DCs led to changes of the gene expression pattern. A variety of pro-inflammatory cytokines and chemokines (CXCL10, CXCL11, CCL5), TLR3 and genes whose products function downstream of the TLR3 signalling pathway (e.g....
ORGANISM(S): Homo sapiens 
2009-08-01 | E-GEOD-14816 | biostudies-arrayexpress
TranscriptomicsGene Expression Profiling of the Retina after Transcorneal Electrical Stimulation in Wildtype Brown Norway Rats
Purpose: To investigate the effect of transcorneal electrical stimulation (TES) on the retina of wildtype Brown Norway (BN) rats by gene expression profiling. Methods: TES was applied to BN adult wildtype rat retina in vivo for 1h (1ms biphasic pulses at 20Hz; current: 200 M-BM-5A). RNA was isolated...
ORGANISM(S): Rattus norvegicus 
2011-11-21 | E-GEOD-26174 | biostudies-arrayexpress
GenomicsWGS of liver cancer in the Japanese population
Hepatocellular carcinoma (HCC) is the third leading cancer-related cause of death and the seventh most common form of cancer worldwide, with an estimate of more than 700,000 new cases each year. The most established risk factors of HCC are chronic HBV and HCV infection. HBV infection is responsible ...
EGAS00001000678 | EGA
TranscriptomicsMetabolic switching in Streptomyces coelicolor Timeseries 1
Background: During the lifetime of a fermenter culture, the soil bacterium S. coelicolor undergoes a major metabolic switch from exponential growth to antibiotic production. We have studied gene expression patterns during this switch, using a specifically designed Affymetrix genechip and a high-reso...
ORGANISM(S): Streptomyces coelicolor 
2010-05-18 | E-GEOD-18489 | biostudies-arrayexpress
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