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TranscriptomicsTranscription profiling of human naive CD8 T cells at 0, 24, 48 and 72h of in vitro culture stimulated with antigen-B7 and with or without IL-12 or IFNa/b
Differentiation of naive CD8 T cells into cytotoxic effector cells requires three distinct signals- antigen (signal 1), costimulation -B7-1 (signal 2) and cytokine, either interleukin-12 or interferon-a/b (signal 3). Interaction of naive CD8 T cells with antigen and B7-1 programs cell division and p...
ORGANISM(S): Mus musculus 
2009-08-01 | E-GEOD-15930 | biostudies-arrayexpress
TranscriptomicsInhibition of phosphodiesterase-4 promotes oligodendrocyte precursor cell differentiation and enhances CNS remyelination
We used transcription-profiling to identify mitogen-activated protein kinase (Mapk) signaling as an important regulator involved in the differentiation of oligodendrocyte progenitor cells (OPCs) into oligodendrocytes. We show in tissue culture that activation of Mapk signaling by elevation of intrac...
ORGANISM(S): Rattus norvegicus 
2013-08-29 | E-GEOD-50042 | biostudies-arrayexpress
UnknownPartnership for Research on Ebola VACcination (PREVAC): protocol of a randomized, double-blind, placebo-controlled phase 2 clinical trial evaluating three vaccine strategies against Ebola in healthy volunteers in four West African countries.
Not available
S-EPMC7823170 | biostudies-literature
UnknownThe landscape of viral associations in human cancers.
Not available
S-EPMC8076016 | biostudies-literature
UnknownDexamethasone in Hospitalized Patients with Covid-19.
Not available
S-EPMC7383595 | biostudies-literature
UnknownEffect of Hydroxychloroquine in Hospitalized Patients with Covid-19.
Not available
S-EPMC7556338 | biostudies-literature
UnknownDivergent mutational processes distinguish hypoxic and normoxic tumours.
Not available
S-EPMC7002770 | biostudies-literature
UnknownComprehensive molecular characterization of mitochondrial genomes in human cancers.
Not available
S-EPMC7058535 | biostudies-literature
UnknownPan-cancer analysis of whole genomes.
Not available
S-EPMC7025898 | biostudies-literature
UnknownHigh-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations.
Not available
S-EPMC7002524 | biostudies-literature
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