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ProteomicsProteometabolomics for unsupervised identification of protein–metabolite interactions
Protein–metabolite interactions play an important role in the cell’s metabolism and many methods have been developed to screen them in vitro. However, few methods can be applied at a large scale and not alter biological state. Here we describe a proteometabolomic approach, using chromatography to ge...
ORGANISM(S): Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) 
2021-04-27 | PXD025571 | Pride
Protein–metabolite interactions Lc-ms/ms 
ModelsLlorénsRico2016 - Effects of cis-Encoded antisense RNAs (asRNAs) - Case2
LlorénsRico2016 - Effects of cis-Encoded antisense RNAs (asRNAs) - Case1 Three putative effects of the asRNAs were considered in this study: in case 1 , the binding of the asRNA to the corresponding mRNA induces degradation of the duplex. In case 2   (this model)   the binding o...
2017-05-18 | MODEL1511170001 | BioModels
ModelsLlorénsRico2016 - Effects of cis-Encoded antisense RNAs (asRNAs) - Case1
LlorénsRico2016 - Effects of cis-Encoded antisense RNAs (asRNAs) - Case1 Three putative effects of the asRNAs were considered in this study: in case 1  (this model) , the binding of the asRNA to the corresponding mRNA induces degradation of the duplex. In case 2, the binding of the ...
2017-05-18 | MODEL1511170000 | BioModels
ModelsLlorénsRico2016 - Effects of cis-Encoded antisense RNAs (asRNAs) - Case3
LlorénsRico2016 - Effects of cis-Encoded antisense RNAs (asRNAs) - Case3 Three putative effects of the asRNAs were considered in this study: in case 1, the binding of the asRNA to the corresponding mRNA induces degradation of the duplex. In case 2, the binding of the asRNA to...
2017-05-18 | MODEL1511170002 | BioModels
TranscriptomicsGene expression profiling of the superior olivary complex using serial analysis of gene expression
SAGE profile of the rat superior olivary complex (SOC). Rats were 60 days old (P60). Keywords: other
ORGANISM(S): Rattus norvegicus 
2004-12-12 | E-GEOD-2063 | biostudies-arrayexpress
MetabolomicsBioaccumulation of therapeutic drugs by human gut bacteria (B.animalis assays)

Bacteria in the gut can modulate the availability and efficacy of therapeutic drugs. Interactions at this level have only recently started to being systematically mapped and the main underlying mechanism proposed is chemical transformation of drugs by microbes (biotransformation). Here, we invest...

2021-07-20 | MTBLS1264 | MetaboLights
MetabolomicsBioaccumulation of therapeutic drugs by human gut bacteria (E.coli;C.saccharolyticum;S.salivarius;E.rectale;L.plantarum;L.lactis assays)

Bacteria in the gut can modulate the availability and efficacy of therapeutic drugs. Interactions at this level have only recently started to being systematically mapped and the main underlying mechanism proposed is chemical transformation of drugs by microbes (biotransformation). Here, we invest...

2021-07-20 | MTBLS1627 | MetaboLights
MetabolomicsBioaccumulation of therapeutic drugs by human gut bacteria: duloxetine accumulation at different concentrations (L.saccharolytica;E.coli assays)

Bacteria in the gut can modulate the availability and efficacy of therapeutic drugs. Interactions at this level have only recently started to being systematically mapped and the main underlying mechanism proposed is chemical transformation of drugs by microbes (biotransformation). Here, we invest...

2021-07-20 | MTBLS1319 | MetaboLights
MetabolomicsBioaccumulation of therapeutic drugs by human gut bacteria (L.saccharolytica;Standards assays)

Bacteria in the gut can modulate the availability and efficacy of therapeutic drugs. Interactions at this level have only recently started to being systematically mapped and the main underlying mechanism proposed is chemical transformation of drugs by microbes (biotransformation). Here, we invest...

2021-07-20 | MTBLS2885 | MetaboLights
MetabolomicsBioaccumulation of therapeutic drugs by human gut bacteria: secreted metabolite analysis (FIA-MS) (C.saccharolyticum;E.coli;L.plantarum;L.lactis;S.salivarius assays)

Bacteria in the gut can modulate the availability and efficacy of therapeutic drugs. Interactions at this level have only recently started to being systematically mapped and the main underlying mechanism proposed is chemical transformation of drugs by microbes (biotransformation). Here, we invest...

2021-07-20 | MTBLS1791 | MetaboLights
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