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TranscriptomicsLongitudinal miRNA sequencing study of HIV/HCV patients after HCV eradication with direct-acting antiviral (DAAs)
We have carried out a longitudinal study of PBMC's miRNA profile in HIV/HCV coinfected patients (n=28) after HCV eradication with DAA and SVR achivement. HIV monoinfected patients (n=16) were used as control. Briefly, peripheral venous blood samples were collected in EDTA tubes, and PBMCs were isol...
ORGANISM(S): Homo sapiens 
2021-11-23 | E-MTAB-10566 | biostudies-arrayexpress
TranscriptomicsAnalysis of microRNA proflie of peripheral blood mononuclear cells (PBMCs) in HIV-1 infected patients under different clinical status respect to hepatitis C virus (HCV) infection.
A total of 117 HIV-1 infected patients were analyzed. These individuals were categorized in three different groups according to their infectious status for HCV: A) HIV+/HCV+ group, (n=45) patients with HIV infection and active HCV-chronic infection naïve to any HCV treatment (positive PCR and positi...
ORGANISM(S): Homo sapiens 
2021-11-23 | E-MTAB-8274 | biostudies-arrayexpress
TranscriptomicsMethylation profiling of normal and cancerous breast cells from human patients and cell lines in a 125 kB region of the HOXA cluster
To evaluate DNA methylation profile associated with breast cancer in 125 kB region of HOXA cluster we analyzed DNA from normal cancerous breast specimens and cell lines. Analysis was performed on the tiling array covering entire HOXA region with 500bp resolution. Immunoprecipitation with anti-methyl...
ORGANISM(S): Homo sapiens 
2006-11-03 | E-MEXP-880 | biostudies-arrayexpress
TranscriptomicsMicroRNAs Profile of HCV Spontaneous Clarified Individuals, Denotes Previous HCV Infection
Hepatitis C virus (HCV) remains a significant public health threat as new 1.75 million HCV infections emerged worldwide. The majority of these infections become persistently infected, while around 30 % spontaneously eliminate the virus. Clinical factors for viral clarification are related to HCV int...
ORGANISM(S): Homo sapiens 
2019-06-21 | E-MTAB-8023 | biostudies-arrayexpress
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