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TranscriptomicsRNA-sequencing of dorsomedial striaum in male Drd2 flox/flox (WT) and Drd2 flox/flox ChAT-Cre+/- (ChI-D2RKO) mice treated with saline or 20 mg/kg of cocaine (ip) 1 hour prior to dissection
Mice were placed in a novel home cage and habituated for 2 hours. They were then injected with saline or cocaine (20 mg/kg ip). After 1 hour, mice were rapidly sacrificed via cervical dislocation, their brains were promptly dissected, and were rapidly frozen in 2-methylbutane. Tissue punches from th...
ORGANISM(S): Mus musculus 
2020-04-22 | E-MTAB-8589 | biostudies-arrayexpress
TranscriptomicsRNA-SEQ of WT and iMSN-D2RKO Parkinson's mice model treated with L-dopa
We analyzed the RNA expression profiles of Parkinson's model (6-hydroxydopamine lesion, 6-OHDA) mice in two different genotypes, WT and iMSN-D2RKO mice. Mutant iMSN-D2RKO mice were generated by mating D2Rflox/flox males with D2Rflox/flox females carrying the CRE under the control of the D1 receptor ...
ORGANISM(S): Mus musculus 
2023-06-06 | E-MTAB-11848 | biostudies-arrayexpress
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