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MetabolomicsATP-binding Cassette Sub-family C Member 5 (ABCC5) Functions as an Efflux Transporter of Glutamate Conjugates and Analogs
The ubiquitous efflux transporter ATP-binding cassette sub-family C member 5 (ABCC5) is present at high levels in the blood-brain barrier, neurons and glia, but its function is not known. Untargeted metabolomic screens revealed that Abcc5-/- mice accumulate endogenous glutamate conjugates in several...
2015-11-02 | MTBLS197 | MetaboLights
UnknownIdentification and expression of human cytomegalovirus transcription units coding for two distinct Fcgamma receptor homologs.
Not available
S-EPMC136976 | biostudies-literature
MetabolomicsLC-MS metabolic profiling of mouse plasma and cell culture medium in relation to ABCC6 expression
Pseudoxanthoma elasticum (PXE) is an autosomal recessive disease characterized by progressive ectopic mineralization of the skin, eyes and arteries, for which no effective treatment exists. PXE is caused by inactivating mutations in the gene encoding ABCC6 (MRP6), an ATP-dependent efflux transporter...
2013-11-14 | MTBLS61 | MetaboLights
MetabolomicsUncovering the Complexity of the Yeast Lipidome by Means of nLC/NSI-MS/MS
Saccharomyces cerevisiae is a eukaryotic model organism widely used for the investigation of fundamental cellular processes and disease mechanisms. Consequently, the lipid landscape of yeast has been extensively investigated and up to this day the lipidome is considered as rather basic. Here, we use...
2021-01-08 | MTBLS2119 | MetaboLights
UnknownPlatelet PD-L1 reflects collective intratumoral PD-L1 expression and predicts immunotherapy response in non-small cell lung cancer.
Not available
S-EPMC8636618 | biostudies-literature
UnknownFemale Gene Networks Are Expressed in Myofibroblast-Like Smooth Muscle Cells in Vulnerable Atherosclerotic Plaques.
Not available
S-EPMC10521798 | biostudies-literature
UnknownTranscriptomic-based clustering of human atherosclerotic plaques identifies subgroups with different underlying biology and clinical presentation.
Not available
S-EPMC10621615 | biostudies-literature
UnknownSex-specific differences in risk factors and outcomes for long-term mechanical ventilation: a longitudinal cohort analysis of claims data.
Not available
S-EPMC12508137 | biostudies-literature
UnknownPaediatric invasive group A streptococcal infections and associations with viral infections in 15 European countries after lifting non-pharmaceutical interventions against SARS-CoV-2: an interrupted time-series analysis.
Not available
S-EPMC12569802 | biostudies-literature
UnknownPrevention of invasive ventilation (PRiVENT)-a prospective, mixed-methods interventional, multicentre study with a parallel comparison group: study protocol.
Not available
S-EPMC10061400 | biostudies-literature
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