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ProteomicsCharacterization of L1 ORF1p macromolecular complexes from Mael-/- mouse testes
piRNA-deficient Maelstrom (Mael) null mice are characterized by a strong upregulation of retrotransposon LINE-1 (L1) in meiotic spermatocytes. This defect turns out in the accumulation of L1 RNA and ORF1p in their cytoplasm and the formation of prominent ribonucleoprotein aggregates. We used 3-month...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-26 | PXD039425 | Pride
Mouse Retrotransposon line-1 Ribonucleoprotein Germ cell Meiosis 
TranscriptomicsMAEL-dependent selective processing of pachytene piRNA precursors and translation of spermiogenic mRNAs
Piwi-interacting small RNAs (piRNAs) of fetal prospermatogonia of mice have been strongly implicated in transposon control. In contrast, little is known about biogenesis and function of abundant piRNAs from adult testes expressed in late spermatocytes and round spermatids. These so-called "pach...
ORGANISM(S): Mus musculus 
2014-07-25 | E-GEOD-50983 | biostudies-arrayexpress
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