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UnknownCooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity.
Not available
S-EPMC10330843 | biostudies-literature
TranscriptomicsTranscription profiling of liver from mice with constitutively active Hypoxia Inducible Factor (HIF-1a and HIF-2a) or inactivated von Hippel-Lindau tumor suppressor gene product (pVHL)
The effects of constitutively active Hypoxia Inducible Factor (HIF) and inactivated von Hippel-Lindau tumor suppressor gene product (pVHL) were examined in a mouse model. Conditionally expressed, constitutively active HIF-1a and HIF-2a were compared with inactivated pVHL.
ORGANISM(S): Mus musculus 
2006-09-21 | E-MEXP-856 | biostudies-arrayexpress
GenomicsIntegrative and comparative genomics identifies the tyrosine kinase FES as a key melanoma tumor supppressor: WGS
An incomplete view of the (epi)genetic events that drive melanoma initiation and progression has been a major barrier to rational development of effective therapeutics and prognostic diagnostics for melanoma patients. Recent approaches that integrate human melanoma genomic and transcriptomic data pr...
ORGANISM(S): Mus musculus 
2017-05-03 | E-MTAB-4921 | biostudies-arrayexpress
GenomicsIntegrative and comparative genomics identifies the tyrosine kinase FES as a key melanoma tumor supppressor: WGS part 2
An incomplete view of the (epi)genetic events that drive melanoma initiation and progression has been a major barrier to rational development of effective therapeutics and prognostic diagnostics for melanoma patients. Recent approaches that integrate human melanoma genomic and transcriptomic data pr...
ORGANISM(S): Mus musculus 
2017-05-03 | E-MTAB-5590 | biostudies-arrayexpress
UnknownMitochondrial DNA Stress Signalling Protects the Nuclear Genome.
Not available
S-EPMC7213273 | biostudies-literature
UnknownPD-L1 methylation regulates PD-L1 expression and is associated with melanoma survival.
Not available
S-EPMC6475614 | biostudies-literature
UnknownPathology of spontaneous and immunotherapy-induced tumor regression in a murine model of melanoma.
Not available
S-EPMC6500596 | biostudies-literature
GenomicsIntegrative and comparative genomics identifies the tyrosine kinase FES as a key melanoma tumor supppressor: WES
An incomplete view of the (epi)genetic events that drive melanoma initiation and progression has been a major barrier to rational development of effective therapeutics and prognostic diagnostics for melanoma patients. Recent approaches that integrate human melanoma genomic and transcriptomic data pr...
ORGANISM(S): Mus musculus 
2017-05-03 | E-MTAB-4917 | biostudies-arrayexpress
UnknownThe hematopoietic stem cell regulatory gene latexin has tumor-suppressive properties in malignant melanoma.
Not available
S-EPMC3683103 | biostudies-literature
UnknownTissue-specific modifier alleles determine Mertk loss-of-function traits.
Not available
S-EPMC9433089 | biostudies-literature
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