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TranscriptomicsBioactive Pyridine-N-oxide Disulfides from Allium stipitatum
In this study, the researchers isolated a colorless waxy solid from the chloroform extract of Allium stipitatum as Compound 1. They demonstrated compound 1 is a potent bactericidal agent against nonreplicating Mycobacterium tuberculosis. Using microarray technology the authors report gene expression...
ORGANISM(S): Mycobacterium tuberculosis 
2009-08-15 | E-GEOD-17640 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of RelE family toxin overexpression in Mycobacterium tuberculosis
To understand the mechanism of action of the RelE family of toxins on metabolism of Mycobacterium tuberculosis. To this effect, toxin expression was induced under control of a tetracycline regulatable promoter and transcriptional profiles compared during overexpression of the three RelE toxin family...
ORGANISM(S): Mycobacterium tuberculosis 
2010-05-18 | E-GEOD-13998 | biostudies-arrayexpress
TranscriptomicsMycobacterium tuberculosis microarray to screen anti-tuberculosis compounds
Feature reduction of microarray data from mycobacteria treated with a variety of various clinical and investigational drugs We are using feature reduction to demonstrate that subsets of biomarker genes representative of the whole genome are sufficient for MOA classification and deconvolution in a me...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2013-04-24 | E-GEOD-46212 | biostudies-arrayexpress
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