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TranscriptomicsGlobal changes in the nuclear positioning of chromatin domains and genomic interactions that orchestrate B cell fate
The genome is folded into domains that are located in either transcriptionally inert or permissive compartments. Here we used genome-wide strategies to characterize domains during B cell development. Structured Interaction Matrix Analysis revealed that CTCF occupancy was primarily associated with i...
ORGANISM(S): Mus musculus 
2012-10-09 | E-GEOD-40173 | biostudies-arrayexpress
GenomicsMus musculus
Brg1 activates enhancer repertoires to establish B cell identity and modulate cell growth
PRJNA278629 | ENA
GenomicsBrg1 activates enhancer repertoires to establish B cell identity and modulate cell growth
Early B cell development is orchestrated by the combined activities of the transcriptional regulators E2A, EBF1, Foxo1 and Ikaros. However, how the genome-wide binding patterns of these regulators are modulated during B-lineage development remains to be determined. Here, we found that in lymphoid pr...
ORGANISM(S): Mus musculus 
2015-05-15 | E-GEOD-66978 | biostudies-arrayexpress
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